HIP14; ZDHHC17 Polyclonal antibody, PBS Only

• Home
• Products
• Primary Antibodies
• HIP14; ZDHHC17 Polyclonal antibody, PBS Only (15465-1-PBS)

• 

  WB analysis of Raji using 15465-1-AP (same clone as 15465-1-PBS)

  Raji cells were subjected to SDS PAGE followed by western blot with 15465-1-AP (HIP14; ZDHHC17 antibody) at dilution of 1:400 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 15465-1-PBS in a different storage buffer formulation.

• 

  WB analysis of human kidney using 15465-1-AP (same clone as 15465-1-PBS)

  human kidney tissue were subjected to SDS PAGE followed by western blot with 15465-1-AP (HIP14; ZDHHC17 antibody) at dilution of 1:400 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 15465-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human testis using 15465-1-AP (same clone as 15465-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human testis using 15465-1-AP (HIP14; ZDHHC17 antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 15465-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human testis using 15465-1-AP (same clone as 15465-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human testis using 15465-1-AP (HIP14; ZDHHC17 antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 15465-1-PBS in a different storage buffer formulation.

HIP14; ZDHHC17 Polyclonal Antibody for WB, IHC, ELISA

Cat No. 15465-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, ELISA

Synonyms

ZDHHC17, Acyltransferase ZDHHC17, DHHC 17, DHHC domain-containing cysteine-rich protein 17, EC:2.3.1.-

---

Product Information

15465-1-PBS targets HIP14; ZDHHC17 in WB, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag7763

  Product name: Recombinant human HIP14; ZDHHC17 protein

  Source: e coli.-derived, PET28a

  Tag: 6*His

  Domain: 1-311 aa of BC050324

  Sequence: MQREEGFNTKMADGPDEYDTEAGCVPLLHPEEIKPQSHYNHGYGEPLGRKTHIDDYSTWDIVKATQYGIYERCRELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVISLLLEAGANVDAQNIKGESALDLAKQRKNVWMINHLQEARQAKGYDNPSFLRKLKADKEFRQKVMLGTPF

• Full Name: zinc finger, DHHC-type containing 17
• Calculated Molecular Weight: 73 kDa
• Observed Molecular Weight: 70 kDa
• GenBank Accession Number: BC050324
• Gene Symbol: ZDHHC17
• Gene ID (NCBI): 23390
• RRID: AB_2217690
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q8IUH5
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

Post-translational modification by the lipid palmitate is crucial for the correct targeting and function of many proteins. Polyglutamine expansions of huntingtin protein are responsible for the Huntington neurological disorder. ZDHHC17 gene encodes palmitoyl transferase huntingtin interacting protein (HIP14) which regulates palmitoylation and distribution of hungtingtin. The latter is implicated in the formation of inclusion bodies and enhanced neuronal toxicity. HIP14 was also shown to control neurotransmitter release.