Validation Data Gallery
|Positive WB detected in
|mouse brain tissue, HeLa cells, mouse lung tissue, mouse heart tissue, human liver tissue, mouse kidney tissue
|Positive IP detected in
|mouse brain tissue
|Positive IHC detected in
|human placenta tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
|Western Blot (WB)
|WB : 1:1000-1:4000
|IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
|IHC : 1:20-1:200
|It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
|Sample-dependent, check data in validation data gallery
16814-1-AP targets HIP1R in WB, IP, IHC, IF, ELISA applications and shows reactivity with human, mouse, rat samples.
|human, mouse, rat
|Host / Isotype
|Rabbit / IgG
|HIP1R fusion protein Ag10353
|huntingtin interacting protein 1 related
|Calculated molecular weight
|615 aa, 70 kDa, 120 kDa
|Observed molecular weight
|GenBank accession number
|Gene ID (NCBI)
|Antigen affinity purification
|PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
|Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.
Targeting Pin1 renders pancreatic cancer eradicable by synergizing with immunochemotherapy.
Nat Cell Biol
Acetylation-dependent regulation of PD-L1 nuclear translocation dictates the efficacy of anti-PD-1 immunotherapy.
Nat Biomed Eng
Inhibiting PD-L1 palmitoylation enhances T-cell immune responses against tumours.
Nat Chem Biol
HIP1R targets PD-L1 to lysosomal degradation to alter T cell-mediated cytotoxicity.
The Huntingtin-interacting protein SETD2/HYPB is an actin lysine methyltransferase.
J Clin Med
HIP1R Expression and Its Association with PD-1 Pathway Blockade Response in Refractory Advanced NonSmall Cell Lung Cancer: A Gene Set Enrichment Analysis.