Anti-Human HLA-G Rabbit Recombinant Antibody

• Home
• Products
• Primary Antibodies
• Flow Cytometry Antibodies
• Anti-Human HLA-G Rabbit Recombinant Antibody (98985-1-RR)

HLA-G Uni-rAb^® Recombinant Antibody for FC

Cat No. 98985-1-RR

Clone No.261668A1

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC

Synonyms

HLAG, HLA-6.0, MHC G, MHCG, Soluble HLA class I histocompatibility antigen, alpha chain G

• 

  FC experiment of JAR using 98985-1-RR

  1x10^6 JAR cells (left) or K562 cells (right) were surface stained with 0.25 ug Anti-Human HLA-G Rabbit RecAb (98985-1-RR, Clone: 261668A1) (red) or 0.25 ug Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed.

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy

---

Tested Applications

• Positive FC detected in: JAR cells

Recommended dilution

• Flow Cytometry (FC): FC : 0.25 ug per 10^6 cells in a 100 µl suspension

This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

98985-1-RR targets HLA-G in FC applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  unknow

• Full Name: major histocompatibility complex, class I, G
• Gene Symbol: HLA-G
• Gene ID (NCBI): 3135
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: P17693
• Storage Buffer: PBS with 0.09% sodium azide, pH 7.3.
• Storage Conditions: Store at 2 - 8°C. Stable for one year after shipment.

Background Information

Human major histocompatibility complex (MHC) antigens, also referred to as human leukocyte antigens (HLA), are encoded by genes located on the short arm of chromosome 6 (6p21.3). HLA-G is a non-classical MHC class I molecule with multiple immunoregulatory properties. HLA-G exhibits a restricted pattern of expression that includes placental extravillous trophoblasts at the maternal-fetal interface, where it abolishes maternal immune cell activity against fetus and establishes immune tolerance. Aberrant expression of HLA-G has been found in a variety of human neoplastic diseases. It plays an important role in the escape of tumor cells from immunosurveillance.