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  • KD/KO Validated

HNRNPA2B1 Polyclonal antibody

HNRNPA2B1 Polyclonal Antibody for IHC, WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, RIP, IHC, IF, ELISA

Conjugate

Unconjugated

Cat no : 14813-1-AP

Synonyms

hnRNP A2/B1, HNRNPA2, HNRNPA2B1, HNRNPB1, HNRPA2, HNRPA2B1, HNRPB1, RNPA2, SNRPB1



Tested Applications

Positive WB detected inA431 cells, A549 cells, Jurkat cells, Raji cells, HL-60 cells, HSC-T6 cells, HeLa cells, K-562 cells
Positive IHC detected inhuman lymphoma tissue, human colon cancer tissue, human cervical cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:2000-1:16000
Immunohistochemistry (IHC)IHC : 1:50-1:500
Sample-dependent, check data in validation data gallery

Product Information

14813-1-AP targets HNRNPA2B1 in WB, RIP, IHC, IF, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen HNRNPA2B1 fusion protein Ag6563
Full Name heterogeneous nuclear ribonucleoprotein A2/B1
Calculated molecular weight 37 kDa
Observed molecular weight 36 kDa and 38 kDa
GenBank accession numberBC000506
Gene symbol HNRNPA2B1
Gene ID (NCBI) 3181
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

HnRNPA2B1 in one of heterogenous nuclear ribonucleoproteins (HnRNPs), which regulate the splicing and transportation of mRNA. It has a role in packaging nascent mRNA, alternative splicing, tycoplamic RNA trafficking, translation and stabilization. Besides it may involve in telomere maintenance, cell proliferation and differentiation, and glucose transport. Gene HURNPA2B1 encode two protein, HNRNPA2 (38kd) and HNRNPB1 (36kd), by alternative splicing.

Protocols

Product Specific Protocols
WB protocol for HNRNPA2B1 antibody 14813-1-APDownload protocol
IHC protocol for HNRNPA2B1 antibody 14813-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
mouseWB

Nature

METTL3 regulates heterochromatin in mouse embryonic stem cells.

Authors - Wenqi Xu
humanWB,IF,RIP

Mol Cancer

CircMYH9 drives colorectal cancer growth by regulating serine metabolism and redox homeostasis in a p53-dependent manner

Authors - Xin Liu
WB

Nat Commun

Profiling PRMT methylome reveals roles of hnRNPA1 arginine methylation in RNA splicing and cell growth.

Authors - Wen-Juan Li
  • KD Validated
mouseRIP

EMBO J

PGE2 -EP3 axis promotes brown adipose tissue formation through stabilization of WTAP RNA methyltransferase.

Authors - Xixi Tao
humanWB,RIP

Mol Ther

Integrative Analysis of NSCLC Identifies LINC01234 as an Oncogenic lncRNA that Interacts with HNRNPA2B1 and Regulates miR-106b Biogenesis.

Authors - Zhenyao Chen
  • KD Validated
humanWB

Hum Mol Genet

Nuclear TDP-43 causes neuronal toxicity by escaping from the inhibitory regulation by hnRNPs.

Authors - Hiroaki Suzuki