Product Information
13513-1-AP targets HOXA1 in WB, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | human, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag4437 Product name: Recombinant human HOXA1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-335 aa of BC032547 Sequence: MDNARMNSFLEYPILSSGDSGTCSARAYPSDHRITTFQSCAVSANSCGGDDRFLVGRGVQIGSPHHHHHHHHHHPQPATYQTSGNLGVSYSHSSCGPSYGSQNFSAPYSPYALNQEADVSGGYPQCAPAVYSGNLSSPMVQHHHHHQGYAGGAVGSPQYIHHSYGQEHQSLALATYNNSLSPLHASHQEACRSPASETSSPAQTFDWMKVKRNPPKTGKVGEYGYLGQPNAVRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGLLPISPATPPGNDEKAEESSEKSSSSPCVPSPGSSTSDTLTTSH Predict reactive species |
| Full Name | homeobox A1 |
| Calculated Molecular Weight | 335 aa, 37 kDa |
| GenBank Accession Number | BC032547 |
| Gene Symbol | HOXA1 |
| Gene ID (NCBI) | 3198 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | P49639 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
HOXA, a member of HOX family, encoded by HOX genes, is a transcriptional factors that plays important role in organogenesis during development via the regualtion of proliferation, differentiation, survival, migration and invasion.HOXA1 influences numerous cellular processes including proliferation, apoptosis, and the epithelial–mesenchymal transition (EMT), and HOXA1 overexpression is sufficient for malignant transformation of nontumorigenic epithelial cells.
Publications
What published studies show
The HOXA1 Polyclonal antibody (Cat# 13513-1-AP) has 4 citations. These appear in Molecular Neurobiology, Oncology Research, Tumour Biology, and European Review for Medical and Pharmacological Sciences. The associated research fields include pain-related neuromodulation in knee osteoarthritis, cervical cancer (miRNA regulation and lncRNA-mediated proliferation), and hepatocellular carcinoma prognosis. Applications cited are primarily Western blot, with one study also using IHC. Species tested include human and rat.
| Species | Application | Title |
|---|---|---|
Mol Neurobiol Verification of Pain-Related Neuromodulation Mechanisms of Calcitonin in Knee Osteoarthritis | ||
Tumour Biol Overexpression of HOXA1 correlates with poor prognosis in patients with hepatocellular carcinoma.
| ||
Eur Rev Med Pharmacol Sci Long non-coding RNA 00152 promotes cell proliferation in cervical cancer via regulating miR-216b-5p/HOXA1 axis. |
