HOXA11 Polyclonal antibody

HOXA11 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IHC, ELISA

Conjugate

Unconjugated

Publications

3

Cat no : 55495-1-AP

Synonyms

homeobox A11, Homeobox protein Hox 1I, Homeobox protein Hox A11, HOX1, HOX1I, HOXA11

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Validation Data Gallery

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  WB analysis of HeLa using 55495-1-AP

  HeLa cells were subjected to SDS PAGE followed by western blot with 55495-1-AP (HOXA11 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

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Tested Applications

• Positive WB detected in: HeLa cells

Recommended dilution

• Western Blot (WB): WB : 1:500-1:2000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Published Applications

• KD/KO: See 2 publications below
• WB: See 3 publications below
• IHC: See 1 publications below

Product Information

55495-1-AP targets HOXA11 in WB, IHC, ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Cited Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: Peptide
• Full Name: homeobox A11
• Calculated Molecular Weight: 34 kDa
• Observed Molecular Weight: 37 kDa
• GenBank Accession Number: NM_005523
• Gene Symbol: HOXA11
• Gene ID (NCBI): 3207
• RRID: AB_2722488
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

HOXA11 belongs to the Abd-B homeobox family. It is a sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Defects in HOXA11 are the cause of radioulnar synostosis with amegakaryocytic thrombocytopenia (RSAT). This antibody is specific to Human/Mouse HOXA11 and Rat Hoxa10.

Publications

Species	Application	Title
human	WB	Cell Physiol Biochem; Long Non-Coding RNA MEG3 Functions as a Competing Endogenous RNA to Regulate HOXA11 Expression by Sponging miR-181a in Multiple Myeloma.; Authors - Xuxing Shen
human	WB,IHC	iScience; HOXA11 promotes lymphatic metastasis of gastric cancer via transcriptional activation of TGFβ1; Authors - Zhenyuan Li ; KD Validated
mouse	WB	Cell Metab; The lncRNA HOXA11os regulates mitochondrial function in myeloid cells to maintain intestinal homeostasis; Authors - Liraz Shmuel-Galia ; KO Validated