HSPG2-Specific Polyclonal antibody

HSPG2-Specific Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 19675-1-AP

Synonyms

heparan sulfate proteoglycan 2, HSPG, HSPG2, HSPG2-Specific, Perlecan, PLC, PRCAN, SJA, SJS, SJS1



Tested Applications

Positive WB detected inCOLO 320 cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Published Applications

WBSee 1 publications below

Product Information

19675-1-AP targets HSPG2-Specific in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Peptide
Full Name heparan sulfate proteoglycan 2
Calculated Molecular Weight 469 kDa
Observed Molecular Weight 469 kDa
GenBank Accession NumberNM_005529
Gene Symbol HSPG2
Gene ID (NCBI) 3339
RRIDAB_10638605
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

HSPG2, also named as PLC and HSPG, is an integral component of basement membranes. It is responsible for the fixed negative electrostatic charge and is involved in the charge-selective ultrafiltration properties. It serves as an attachment substrate for cells. Defects in HSPG2 are the cause of Schwartz-Jampel syndrome (SJS1). Defects in HSPG2 are the cause of dyssegmental dysplasia Silverman-Handmaker type (DDSH). The antibody is specific to HSPG2.

Protocols

Product Specific Protocols
WB protocol for HSPG2-Specific antibody 19675-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB

Int J Biol Sci

Exosomal Transfer of Vasorin Expressed in Hepatocellular Carcinoma Cells Promotes Migration of Human Umbilical Vein Endothelial Cells.

Authors - Aixue Huang