Product Information
19959-1-AP targets HTR2C in WB, ELISA applications and shows reactivity with human, mouse samples.
| Tested Reactivity | human, mouse |
| Cited Reactivity | mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
Peptide Predict reactive species |
| Full Name | 5-hydroxytryptamine (serotonin) receptor 2C |
| Calculated Molecular Weight | 52 kDa |
| GenBank Accession Number | NM_000868 |
| Gene Symbol | HTR2C |
| Gene ID (NCBI) | 3358 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | P28335 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
HTR2C, also named HTR1C, belongs to the G-protein coupled receptor 1 family. HTR2C is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. It mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. It is glycosylated at N-term. The antibody recognizes the C-term of HTR2C.
Publications
What published studies show
The HTR2C Polyclonal antibody (Cat# 19959-1-AP) has 1 citation. It was used in Western Blot in a study published in eLife (2025), investigating how glutamine catabolism supports amino acid biosynthesis and suppresses the integrated stress response to promote photoreceptor survival. The research falls within the fields of neuroscience, metabolic regulation, and retinal cell biology.
| Species | Application | Title |
|---|---|---|
Elife Glutamine catabolism supports amino acid biosynthesis and suppresses the integrated stress response to promote photoreceptor survival |
