HuR/ELAVL1 Recombinant monoclonal antibody, PBS Only

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  WB analysis using 82690-2-RR (same clone as 82690-2-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 82690-2-RR (HuR/ELAVL1 antibody) at dilution of 1:2500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82690-2-PBS in a different storage buffer formulation.

HuR/ELAVL1 Uni-rAb^® Recombinant Antibody for WB, Indirect ELISA

Cat No. 82690-2-PBS

Clone No.4L10

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Synonyms

ELAVL1, Hu antigen R, ELAV-like protein 1, ELAVL 1, ELAV1

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Product Information

82690-2-PBS targets HuR/ELAVL1 in WB, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  CatNo: Ag2249

  Product name: Recombinant human HuR protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 1-326 aa of BC003376

  Sequence: MSNGYEDHMAEDCRGDIGRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAINTLNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPNQNKNVALLSQLYHSPARRFGGPVHHQAQRFRFSPMGVDHMSGLSGVNVPGNASSGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLNGYRLGDKILQVSFKTNKSHK

• Full Name: ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)
• Calculated Molecular Weight: 326 aa, 36 kDa
• Observed Molecular Weight: 30-37 kDa
• GenBank Accession Number: BC003376
• Gene Symbol: HuR/ELAVL1
• Gene ID (NCBI): 1994
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: Q15717
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

ELAVL1, also named as HUR, belongs to the RRM elav family. It is involved in 3'-UTR ARE-mediated MYC stabilization. ELAVL1 binds avidly to the AU-rich element in FOS and IL3/interleukin-3 mRNAs. In the case of the FOS AU-rich element, ELAVL1 binds to a core element of 27 nucleotides that contain AUUUA, AUUUUA and AUUUUUA motifs.