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IFITM1 Polyclonal antibody
IFITM1 Polyclonal Antibody for FC, IHC, IP, WB,ELISA
Cat no : 11727-3-AP
Validation Data Gallery
|Positive WB detected in
|HepG2 cells, K-562 cells
|Positive IP detected in
|Positive IHC detected in
|human lymphoma tissue, mouse brain tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
|Positive FC detected in
|Western Blot (WB)
|WB : 1:500-1:1000
|IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
|IHC : 1:50-1:500
|Flow Cytometry (FC)
|FC : 0.20 ug per 10^6 cells in a 100 µl suspension
|It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
|Sample-dependent, check data in validation data gallery
11727-3-AP targets IFITM1 in WB, IP, IHC, IF, FC, ELISA applications and shows reactivity with human, rat, mouse samples.
|human, rat, mouse
|human, goat, African green monkey
|Host / Isotype
|Rabbit / IgG
|IFITM1 fusion protein Ag2320
|interferon induced transmembrane protein 1 (9-27)
|Calculated molecular weight
|Observed molecular weight
|GenBank accession number
|Gene ID (NCBI)
|Antigen affinity purification
|PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
|Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.
IFITM1(interferon induced transmembrane protein), also named DSPA2a or interferon-induced protein 17 (IFI17), belongs to the CD225 family. It has two transmembrane domain and serves as an IFN-induced antiviral protein that mediates cellular innate immunity to at least three major human pathogens, influenza A H1N1 virus, West Nile virus (WNV), and dengue virus , by inhibiting the early steps of replication. IFITM proteins are recently identified as viral restriction factors that inhibit infection mediated by the influenza A virus (IAV) hemagglutinin (HA) protein. Also they serve as important components of the innate immune system to restrict HIV-1 infection.
|Product Specific Protocols
|WB protocol for IFITM1 antibody 11727-3-AP
|IHC protocol for IFITM1 antibody 11727-3-AP
|IP protocol for IFITM1 antibody 11727-3-AP
|FC protocol for IFITM1 antibody 11727-3-AP
|Click here to view our Standard Protocols
Mitotic progression following DNA damage enables pattern recognition within micronuclei.
Intrinsic retroviral reactivation in human preimplantation embryos and pluripotent cells.
Exosomes mediate the cell-to-cell transmission of IFN-α-induced antiviral activity.
Type 1 Interferon Responses Underlie Tumor-Selective Replication of Oncolytic Measles Virus.
IFITM3 restricts virus-induced inflammatory cytokine production by limiting Nogo-B mediated TLR responses
IFITM Proteins Restrict HIV-1 Infection by Antagonizing the Envelope Glycoprotein.