Anti-Human IFNAR1 Rabbit Recombinant Antibody, PBS Only

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  FC experiment of U-937 using 98067-1-RR (same clone as 98067-1-PBS)

  1x10^6 U-937 cells were surface stained with 0.25 ug Anti-Human IFNAR1 Rabbit Recombinant Antibody (98067-1-RR, Clone:230549B1) and PE-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L)(red), or 0.25 ug Isotype Control (blue). Cells were not fixed. This data was developed using the same antibody clone with 98067-1-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 98067-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98067-1-RR against Human IFNAR1 were performed. The affinity constant is 1.15 nM.

IFNAR1 Uni-rAb^® Recombinant Antibody for FC

Cat No. 98067-1-PBS

Clone No.230549B1

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC

Synonyms

IFN alpha REC, Cytokine receptor class-II member 1, CRF2-1, CRF2 1, AVP

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Product Information

98067-1-PBS targets IFNAR1 in FC applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  Recombinant protein

• Full Name: interferon (alpha, beta and omega) receptor 1
• Calculated Molecular Weight: 557 aa, 64 kDa
• GenBank Accession Number: BC021825
• Gene Symbol: IFNAR1
• Gene ID (NCBI): 3454
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• UNIPROT ID: P17181
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

Interferon alpha and beta receptor subunit 1 (IFNAR1) is a type I membrane protein that associates with IFNAR2 to form the receptor for type I interferons, including interferons-alpha, -beta, and -lambda. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2, and then increase transcription of the IFN-induced genes whose products exert antiviral, immunomodulatory, and antiproliferative effects.