Product Information
16759-1-PBS targets IGDCC3 in IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag10276 Product name: Recombinant human IGDCC3 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 37-401 aa of BC067107 Sequence: GHSAELAFAVEPSDDVAVPGQPIVLDCRVEGTPPVRITWRKNGVELPESTHSTLLANGSLMIRHFRLEPGGSPSDEGDYECVAQNRFGLVVSRKARIQAATMSDFHVHPQATVGEEGGVARFQCQIHGLPKPLITWEKNRVPIDTDNERYTLLPKGVLQITGLRAEDGGIFHCVASNIASIRISHGARLTVSGSGSGAYKEPAILVGPENLTLTVHQTAVLECVATGNPRPIVSWSRLDGRPIGVEGIQVLGTGNLIISDVTVQHSGVYVCAANRPGTRVRRTAQGRLVVQAPAEFVQHPQSISRPAGTTAMFTCQAQGEPPPHVTWLKNGQVLGPGGHVRLKNNNSTLTISGIGPEDEAIYQCV Predict reactive species |
| Full Name | immunoglobulin superfamily, DCC subclass, member 3 |
| Calculated Molecular Weight | 814 aa, 87 kDa |
| Observed Molecular Weight | 87 kDa |
| GenBank Accession Number | BC067107 |
| Gene Symbol | IGDCC3 |
| Gene ID (NCBI) | 9543 |
| RRID | AB_3669255 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q8IVU1 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
IGDCC3, also known as PUNC, is a transmembrane protein that belongs to the immunoglobulin (Ig) superfamily (PMID: 9507132). IGDCC3 contains 4 C2-type Ig-like domains and 2 fibronectin type III repeats. It is highly expressed in the developing embryo in nervous system, limbs, and inner ear (PMID: 9922388; 9507132). IGDCC3 may be involved in the cerebellar control of motor coordination (PMID: 11486040). It has also been associated with tumorigenic mechanism and prognosis of cholangiocarcinoma (PMID: 36979826).
