Product Information
25095-1-PBS targets IGFN1 in WB, Indirect ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag18731 Product name: Recombinant human IGFN1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 42-385 aa of BC131529 Sequence: IYGERRDATRSSTSRYKPGTGSFSKDAQGPMGHFSQGLADMEVQPGEAATLSCTLTSDLGPGTWFKDGVKLTTQDGVIFKQDGLVHSLFITHVQGTQAGRYTFVAGDQQSEATLTVQDSPTIAPDVTEKLREPLVVKAGKPVIVKIPFQSHLPIQAAWRKDGAEVVGSSDREAQVDLGDGYTRLCLPSAGRKDCGQYSVTLRSEGGSVQAELTLQVIDKPDPPQGPMEVQDCHRAGVCLRWRPPRDNGGRTVECYVVERRQAGRSTWLKVGEAPADSTTFTDAHVEPGRKYTFRVRAVTSEGAGEALESEEILVAPEALPKAPSAPAILSASSQGITLTWTAPR Predict reactive species |
| Full Name | immunoglobulin-like and fibronectin type III domain containing 1 |
| Calculated Molecular Weight | 1251 aa, 138 kDa |
| Observed Molecular Weight | 100 kDa |
| GenBank Accession Number | BC131529 |
| Gene Symbol | IGFN1 |
| Gene ID (NCBI) | 91156 |
| RRID | AB_3669462 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q86VF2 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
Immunoglobulin-like and fibronectin type III domain-containing protein 1 (IGFN1), also known as EEF1A2-binding protein 1 (EEF1A2BP1) or KY-interacting protein 1 (KYIP1), presents structural similarity to sarcomeric proteins belonging to the intracellular Ig superfamily, including myosin-binding protein C fast and slow-type skeletal muscle isoforms (PMID: 18756455). IGFN1 along with KY and FLNC is the part of a Z-band associated protein complex likely providing structural support to the skeletal muscle (PMID: 20206623). IGFN1 gene has been associated with some cancers (PMID: 28027327; 30335789; 35456975). At least five isoforms of IGFN1 produced by alternative splicing have been identified (PMID: 20206623).
