IHCeasy HDAC3 Ready-To-Use IHC Kit
HDAC3 Ready-to-use reagent kit for IHC.
Cat no : KHC0614
HD3, HDAC3, histone deacetylase 3, RPD3, RPD3 2, SMAP45
KHC0614 is a ready-to-use IHC kit for staining of HDAC3. The kit provides all reagents, from antigen retrieval to cover slip mounting, that require little to no diluting or handling prior to use. Simply apply the reagents to your sample slide according to the protocol and you're steps away from obtaining high-quality IHC data.
|Product name||IHCeasy HDAC3 Ready-To-Use IHC Kit|
|Sample type||FFPE tissue|
|Primary antibody type||Rabbit Polyclonal|
|Secondary antibody type||Polymer-HRP-Goat anti-Rabbit|
|Antigen Retrieval Buffer||100 mL||50×|
|Washing Buffer||100 mL ×2||20×|
|Blocking Buffer||5 mL||RTU|
|Primary Antibody||5 mL||RTU|
|Secondary Antibody||5 mL||RTU|
|Chromogen Component A||0.2 mL||RTU|
|Chromogen Component B||4 mL||RTU|
|Signal Enhancer||5 mL||RTU|
|Counter Staining Reagent||5 mL||RTU|
|Mounting Media||5 mL||RTU|
Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. Histone deacetylase (HDAC) and histone acetyltransferase (HAT) are enzymes that regulate transcription by selectively deacetylating or acetylating the (-amino groups of lysines located near the amino termini of core histone proteins. At least 4 classes of HDAC were identified. HDAC3 is a class I HDAC. HDAC3 has histone deacetylase activity and may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. HDAC3 can also down-regulate p53 function and thus modulate cell growth and apoptosis. The gene encoding HDAC3 is regarded as a potential tumor suppressor gene.
|Storage Instructions||All the reagents are stored at 2-8°C. The kit is stable for 6 months from the date of receipt.|
|Synonyms||HD3, HDAC3, histone deacetylase 3, RPD3, RPD3 2, SMAP45|