Product Information
32055-1-PBS targets IL-17RA in WB, Indirect ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Eg2317 Product name: Recombinant Human IL-17RA protein (rFc Tag) Source: mammalian cells-derived, pHZ-KIsec-C-rFc Tag: C-rFc Domain: 33-320 aa of BC011624 Sequence: LRLLDHRALVCSQPGLNCTVKNSTCLDDSWIHPRNLTPSSPKDLQIQLHFAHTQQGDLFPVAHIEWTLQTDASILYLEGAELSVLQLNTNERLCVRFEFLSKLRHHHRRWRFTFSHFVVDPDQEYEVTVHHLPKPIPDGDPNHQSKNFLVPDCEHARMKVTTPCMSSGSLWDPNITVETLEAHQLRVSFTLWNESTHYQILLTSFPHMENHSCFEHMHHIPAPRPEEFHQRSNVTLTLRNLKGCCRHQVQIQPFFSSCLNDCLRHSATVSCPEMPDTPEPIPDYMPLW Predict reactive species |
| Full Name | interleukin 17 receptor A |
| Calculated Molecular Weight | 866 aa, 96 kDa |
| Observed Molecular Weight | 100 kDa |
| GenBank Accession Number | BC011624 |
| Gene Symbol | IL17RA |
| Gene ID (NCBI) | 23765 |
| RRID | AB_3670179 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity Purification |
| UNIPROT ID | Q96F46 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
Interleukin-17 receptor A (IL17A) is a major effector cytokine of the innate and adaptive immune system and is involved in antimicrobial host defense and maintenance of tissue integrity. It has been shown that IL-17A is involved in the pathogenesis of asthma and allergy and regulates local immune and inflammatory processes in bone tissue and is involved in the onset and progression of osteoporosis. In addition to this, due to polymorphisms in the IL17RA gene, it leads to the development of Fanconi anemia.
