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- KD/KO Validated
IL-33 Polyclonal antibody
IL-33 Polyclonal Antibody for IHC,ELISA
Host / Isotype
Rabbit / IgG
human and More (2)
WB, IHC, IF, ELISA
Cat no : 12372-1-AP
|Positive IHC detected in||human tonsillitis tissue|
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
|Immunohistochemistry (IHC)||IHC : 1:200-1:800|
|Sample-dependent, check data in validation data gallery|
|KD/KO||See 1 publications below|
|WB||See 12 publications below|
|IHC||See 12 publications below|
|IF||See 3 publications below|
|ELISA||See 1 publications below|
12372-1-AP targets IL-33 in WB, IHC, IF, ELISA applications and shows reactivity with human samples.
|Cited Reactivity||human, mouse, rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||IL-33 fusion protein Ag2957|
|Full Name||interleukin 33|
|Calculated molecular weight||30 kDa|
|GenBank accession number||BC047085|
|Gene ID (NCBI)||90865|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.|
IL-33 is an IL-1 family cytokine and nuclear alarmin, is constitutively expressed in epithelial barrier tissues and human blood vessels. IL-33 is involved in the maturation of Th2 cells and the activation of mast cells, basophils, eosinophils and natural killer cells. It also acts as a chemoattractant for Th2 cells, and may function as an "alarmin", that amplifies immune responses during tissue injury.
|Product Specific Protocols|
|WB protocol for IL-33 antibody 12372-1-AP||Download protocol|
|IHC protocol for IL-33 antibody 12372-1-AP||Download protocol|
|Click here to view our Standard Protocols|
J Invest Dermatol
Increased Type 2 Innate Lymphoid Cells in Patients with Drug Reaction with Eosinophilia and Systemic Symptoms Syndrome.
Emodin Alleviates Sodium Taurocholate-Induced Pancreatic Acinar Cell Injury via MicroRNA-30a-5p-Mediated Inhibition of High-Temperature Requirement A/Transforming Growth Factor Beta 1 Inflammatory Signaling.
Free fatty acid receptor 4 deletion attenuates colitis by modulating Treg Cells via ZBED6-IL33 pathway.
Topical application of imatinib mesylate suppresses vitamin D3 analog-induced dermatitis in Balb/c mice
Akkermansia muciniphila Alters Gut Microbiota and Immune System to Improve Cardiovascular Diseases in Murine Model.
Effects of IL-33 on 3T3-L1 cells and obese mice models induced by a high-fat diet.