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  • KD/KO Validated

IL-33 Polyclonal antibody

IL-33 Polyclonal Antibody for IHC,ELISA

Host / Isotype

Rabbit / IgG


human and More (2)





Cat no : 12372-1-AP


C9orf26, DVS27, IL 1F11, IL 33, IL1F11, IL33, IL-33, Interleukin 1 family member 11, interleukin 33, NF HEV, NFEHEV, NFHEV, RP11 575C20.2

Tested Applications

Positive IHC detected inhuman tonsillitis tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

Immunohistochemistry (IHC)IHC : 1:200-1:800
Sample-dependent, check data in validation data gallery

Product Information

12372-1-AP targets IL-33 in WB, IHC, IF, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Cited Reactivityhuman, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen IL-33 fusion protein Ag2957
Full Name interleukin 33
Calculated molecular weight 30 kDa
GenBank accession numberBC047085
Gene symbol IL33
Gene ID (NCBI) 90865
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

IL-33 is an IL-1 family cytokine and nuclear alarmin, is constitutively expressed in epithelial barrier tissues and human blood vessels. IL-33 is involved in the maturation of Th2 cells and the activation of mast cells, basophils, eosinophils and natural killer cells. It also acts as a chemoattractant for Th2 cells, and may function as an "alarmin", that amplifies immune responses during tissue injury.


Product Specific Protocols
WB protocol for IL-33 antibody 12372-1-APDownload protocol
IHC protocol for IL-33 antibody 12372-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols



J Exp Clin Cancer Res

Tobacco smoke induced hepatic cancer stem cell-like properties through IL-33/p38 pathway.

Authors - Chunfeng Xie

Clin Exp Dermatol

Interleukin-33 affects cytokine production by keratinocytes in vitiligo.

Authors - P Li

Int J Neurosci

Overexpression of interleukin-33 is associated with poor prognosis of patients with glioma.

Authors - Jianfei Zhang

BMC Microbiol

Global secretome characterization of A549 human alveolar epithelial carcinoma cells during Mycoplasma pneumoniae infection.

Authors - Shuxian Li

Mediators Inflamm

Decreased IL-33 Production Contributes to Trophoblast Cell Dysfunction in Pregnancies with Preeclampsia.

Authors - Hong Chen
  • KD Validated

J Ethnopharmacol

Khasianine ameliorates psoriasis-like skin inflammation and represses TNF-α/NF-κB axis mediated transactivation of IL-17A and IL-33 in keratinocytes.

Authors - Yixi Yang