ILT-3/LILRB4 Recombinant antibody

• 

  WB analysis of A549 using 86142-1-RR

  A549 cells were subjected to SDS PAGE followed by western blot with 86142-1-RR (ILT-3/LILRB4 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours.

• 

  WB analysis of mouse lung using 86142-1-RR

  mouse lung tissue were subjected to SDS PAGE followed by western blot with 86142-1-RR (ILT-3/LILRB4 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours.

ILT-3/LILRB4 Uni-rAb^TM Recombinant Antibody for WB, ELISA

Cat No. 86142-1-RR

Clone No.250356F3

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

Synonyms

LILRB4, B4, CD85 antigen-like family member K, CD85k, ILT3

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Tested Applications

• Positive WB detected in: A549 cells, mouse lung tissue

Recommended dilution

• Western Blot (WB): WB : 1:2000-1:10000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

86142-1-RR targets ILT-3/LILRB4 in applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: ILT-3/LILRB4 fusion protein Eg1743
• Full Name: leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
• Calculated Molecular Weight: 49kDa
• Observed Molecular Weight: 49 kDa
• GenBank Accession Number: AAH26309.1
• Gene Symbol: LILRB4
• Gene ID (NCBI): 11006
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: Q8NHJ6
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

LILRB4 is an inhibitory receptor in the LILR family mainly expressed on normal and malignant human cells of myeloid origin. LILRB4 is activated and subsequently recruits adaptors to cytoplasmic immunoreceptor tyrosine inhibitory motifs to initiate different signaling cascades, thus playing an important role in physiological and pathological conditions, including autoimmune diseases, microbial infections, and cancers.