- Featured Product
- KD/KO Validated
Inhibin Beta A Polyclonal antibody
Inhibin Beta A Polyclonal Antibody for IF, IHC, WB, ELISA
Host / Isotype
Rabbit / IgG
human and More (3)
WB, IHC, IF, ELISA
Cat no : 10651-1-AP
Validation Data Gallery
|Positive WB detected in||HeLa cells, MCF-7 cells, A549 cells, SGC-7901 cells, BGC-823 cells, HepG2 cells|
|Positive IHC detected in||human lung cancer tissue|
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
|Positive IF detected in||A549 cells|
|Western Blot (WB)||WB : 1:500-1:1000|
|Immunohistochemistry (IHC)||IHC : 1:20-1:200|
|Immunofluorescence (IF)||IF : 1:20-1:200|
|Sample-dependent, check data in validation data gallery|
|KD/KO||See 1 publications below|
|WB||See 4 publications below|
|IHC||See 10 publications below|
|IF||See 2 publications below|
10651-1-AP targets Inhibin Beta A in WB, IHC, IF, ELISA applications and shows reactivity with human samples.
|Cited Reactivity||human, mouse, Hu Sheep, sheep|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Inhibin Beta A fusion protein Ag1001|
|Full Name||inhibin, beta A|
|Calculated molecular weight||47 kDa|
|Observed molecular weight||47 kDa|
|GenBank accession number||BC007858|
|Gene ID (NCBI)||3624|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.|
Inhibin is a 32-kD dimeric glycoprotein consisting of an alpha subunit and one of two beta subunits (beta A or beta B) leading to inhibin A or B, respectively, which was isolated and cloned on the basis of its ability to inhibit FSH release from the pituitary. Inhibin beta A forms a disulfide-linked homo-dimer known as activin A, which has been implicated in multiple biologic processes, including neoplastic progression. The inhibin beta A can also bind the beta B and A isoforms to form activin AB and inhibin, respectively.
|Product Specific Protocols|
|WB protocol for Inhibin Beta A antibody 10651-1-AP||Download protocol|
|IHC protocol for Inhibin Beta A antibody 10651-1-AP||Download protocol|
|IF protocol for Inhibin Beta A antibody 10651-1-AP||Download protocol|
|Click here to view our Standard Protocols|
Homophilic ATP1A1 binding induces activin A secretion to promote EMT of tumor cells and myofibroblast activation.
Combinatorial actions of Tgfβ and Activin ligands promote oligodendrocyte development and CNS myelination.
Action mechanism of inhibin α-subunit on the development of Sertoli cells and first wave of spermatogenesis in mice.
Multiregion single cell analysis reveals a novel subtype of cancer-associated fibroblasts located in the hypoxic tumor microenvironment in colorectal cancer
Activin A is a prominent autocrine regulator of hepatocyte growth arrest.
Esophageal squamous cell carcinoma invasion is inhibited by Activin A in ACVRIB-positive cells.