• Featured Product
  • KD/KO Validated

INO80 Polyclonal antibody

INO80 Polyclonal Antibody for WB,ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IP, IF, ChIP,ELISA

Conjugate

Unconjugated

Cat no : 18810-1-AP

Synonyms

hINO80, INO80, INO80 homolog (S. cerevisiae), INO80A, INOC1, KIAA1259



Tested Applications

Positive WB detected inHeLa cells, mouse brain tissue, mouse liver tissue

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
Sample-dependent, check data in validation data gallery

Product Information

18810-1-AP targets INO80 in WB, IP, IF, ChIP,ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivity human, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Peptide
Full Name INO80 homolog (S. cerevisiae)
Calculated molecular weight 1556 aa, 177 kDa
Observed molecular weight 178 kDa
GenBank accession numberBC146785
Gene symbol INO80
Gene ID (NCBI) 54617
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

INO80, also named as INOC1 and KIAA1259, belongs to the SNF2/RAD54 helicase family. The INO80 complex remodels chromatin by shifting nucleosomes. INO80 recruited by YY1 to YY1-activated INO80. In vitro, INO80 has double stranded DNA-dependent ATPase activity

Protocols

Product Specific Protocols
WB protocol for INO80 antibody 18810-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB

Life Sci Alliance

BZLF1 interacts with chromatin remodelers promoting escape from latent infections with EBV.

Authors - Marisa Schaeffner
  • KD Validated
IF

Biol Reprod

The Mouse INO80 Chromatin Remodeling Complex Is an Essential Meiotic Factor for Spermatogenesis.

Authors - Daniel W Serber
  • KO Validated
humanWB, IF

J Cell Mol Med

INO80 participates in the pathogenesis of recurrent miscarriage by epigenetically regulating trophoblast migration and invasion.

Authors - Shu Xian
humanWB

Oncotarget

Ino80 promotes cervical cancer tumorigenesis by activating Nanog expression.

Authors - Jing Hu
  • KD Validated
chip

Oncogene

INO80 is required for oncogenic transcription and tumor growth in non-small cell lung cancer.

Authors - S Zhang
mouseWB

BMC Biol

Ino80 is essential for proximal-distal axis asymmetry in part by regulating Bmp4 expression.

Authors - Zhijun Qiu
  • KO Validated