INSRR Polyclonal antibody, PBS Only

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• INSRR Polyclonal antibody, PBS Only (55112-1-PBS)

• 

  WB analysis of mouse kidney using 55112-1-AP (same clone as 55112-1-PBS)

  mouse kidney tissue were subjected to SDS PAGE followed by western blot with 55112-1-AP (INSRR antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55112-1-PBS in a different storage buffer formulation.

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  WB analysis of human brain using 55112-1-AP (same clone as 55112-1-PBS)

  human brain tissue were subjected to SDS PAGE followed by western blot with 55112-1-AP (INSRR antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55112-1-PBS in a different storage buffer formulation.

INSRR Polyclonal Antibody for WB, Indirect ELISA

Cat No. 55112-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Synonyms

EC:2.7.10.1, Insulin receptor-related protein, Insulin receptor-related protein alpha chain, Insulin receptor-related protein beta chain, IR related receptor

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Product Information

55112-1-PBS targets INSRR in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  Peptide

• Full Name: IR related receptor
• Calculated Molecular Weight: 144 kDa
• Observed Molecular Weight: 150-155 kDa
• GenBank Accession Number: NM_014215
• Gene Symbol: INSRR
• Gene ID (NCBI): 3645
• RRID: AB_10859077
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: P14616
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

INSRR, also named as IRR, belongs to the protein kinase superfamily, Tyr protein kinase family and INS receptor subfamily. It probably binds an INS related protein and has a tyrosine-protein kinase activity. It phosphorylates the INS receptor substrates IRS-1 and IRS-2. INSRR is a heterotetrameric transmembrane receptor composed of two alpha and two beta chains linked by disulfide bonds. INSRR shares high homology with the INS (IR) and the IGF-1R, but doesn't bind any of IR and IGF-1R known ligands. The antibody is specific to INSRR.