Product Information
22411-1-PBS targets IQSEC3 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag18117 Product name: Recombinant human IQSEC3 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-185 aa of BC024764 Sequence: MESLLENPVRAVLYLKELTAIVQNQQSLIHSQRERIDELERRLDELSAENRSLWEHQQLLQAQPPPGLVPPSSAPLPAAPATAPAAAARAQEPLQDQGQRSAAAPHPAPDRPPRQHHGQLLEQPQRGPGSRAHTPQSPHKHLGTQGAVTDKEKERPPSCCAAAGALLQHKSPSALGKGVLSRRPE Predict reactive species |
| Full Name | IQ motif and Sec7 domain 3 |
| Calculated Molecular Weight | 1182 aa, 128 kDa |
| Observed Molecular Weight | 128 kDa |
| GenBank Accession Number | BC024764 |
| Gene Symbol | IQSEC3 |
| Gene ID (NCBI) | 440073 |
| RRID | AB_3085697 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen Affinity purified |
| UNIPROT ID | Q9UPP2 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
IQSEC3, a gephyrin-binding GABAergic (gamma-aminobutyric acidergic) synapse-specific guanine nucleotide exchange factor, is expressed specifically in the adult brain, predominantly in the cerebral cortex and the olfactory bulb, but not in the fetal brain. IQSEC3 was recently reported to regulate activity-dependent GABAergic synapse maturation,
