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IQUB Polyclonal antibody, PBS Only (25605-1-PBS)

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IP experiment of mouse testis using 25605-1-AP (same clone as 25605-1-PBS)
IP result of anti-IQUB (IP:25605-1-AP, 4ug; Detection:25605-1-AP 1:500) with mouse testis tissue lysate 1120 ug. This data was developed using the same antibody clone with 25605-1-PBS in a different storage buffer formulation.
IP experiment of mouse spleen using 25605-1-AP (same clone as 25605-1-PBS)
IP result of anti-IQUB (IP:25605-1-AP, 4ug; Detection:25605-1-AP 1:500) with mouse spleen tissue lysate 1920 ug. This data was developed using the same antibody clone with 25605-1-PBS in a different storage buffer formulation.
IHC staining of mouse testis using 25605-1-AP (same clone as 25605-1-PBS)
Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 25605-1-AP (IQUB antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 25605-1-PBS in a different storage buffer formulation.
IHC staining of mouse testis using 25605-1-AP (same clone as 25605-1-PBS)
Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 25605-1-AP (IQUB antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 25605-1-PBS in a different storage buffer formulation.

IQUB Polyclonal antibody, PBS Only

Name: IQUB Polyclonal antibody, PBS Only
Brand: Proteintech
SKU: 25605-1-PBS

IQUB Polyclonal Antibody for IHC, IP, Indirect ELISA

Cat No. 25605-1-PBS

Review Product

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

IHC, IP, Indirect ELISA

Synonyms

Formulation: PBS Only

PBS, Azide, Glycerol

Conjugate: Unconjugated

Size/Concentration:

-/ -

Freight/Packing: -

Quantity

- +

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Overview

Tested Applications
Product Information

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MSDS SDS

Product Information

25605-1-PBS targets IQUB in IHC, IP, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity	human, mouse
Host / Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	CatNo: Ag19507 Product name: Recombinant human IQUB protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-350 aa of BC128181 Sequence: MSNQQEKYEAQNIVNSTEESDDAFDTVTIPVPSEEPQESDQTEEHESGIEQFSESHAIHVEEQSDQSFSSLEPDNEQLMEEVISPRQVSYTPQHHEKQYAMQRPNDDSLAFLDKIKSVKESLQESVEDSLATVKVVLIPVGQEIVIPFKVDTILKYLKDHFSHLLGIPHSVLQIRYSGKILKNNETLVQHGVKPQEIVQVEIFSTNPDLYPVRRIDGLTDVSQIITVTVQTGLDQYQQVPVEIVKSDFHKPFLGGFRHKVTGVEYHNAGTQTVPKRIPERLSIFCRDTQTVFQKKNLQQTTNTTSTQMTNIGVYVSNMTDKLVTPGKYFSAAEYHAQRLKAVIVIQTYYR Predict reactive species
Full Name	IQ motif and ubiquitin domain containing
Calculated Molecular Weight	791 aa, 93 kDa
Observed Molecular Weight	70 kDa
GenBank Accession Number	BC128181
Gene Symbol	IQUB
Gene ID (NCBI)	154865
RRID	AB_3085807
Conjugate	Unconjugated
Form	Liquid
Purification Method	Antigen affinity purification
UNIPROT ID	Q8NA54
Storage Buffer	PBS only, pH 7.3.
Storage Conditions	Store at -80°C.

Background Information

IQUB (IQ motif and ubiquitin domain containing) was discovered in 2002,4 which was located on chromosome 7q31.32 and its encoded protein mainly contained 2 domains, ubiquitin-like domain and IQ domain. IQUB had apparently higher expression in breast cancer than that in normal tissues, suggesting that it may act an important role in the occurrence and development of breast cancer (PMID: 29968965). IQUB is a critical RS1 adaptor in mouse sperm flagella, and is critical for sperm motility and fertilization (PMID: 36417862).