IRF9 Recombinant antibody, PBS Only

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  WB analysis using 85160-2-RR (same clone as 85160-2-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85160-2-RR (IRF9 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85160-2-PBS in a different storage buffer formulation.

IRF9 Uni-rAb^TM Recombinant Antibody for WB, Indirect ELISA

Cat No. 85160-2-PBS

Clone No.242772F12

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Synonyms

242772F12, IFN-alpha-responsive transcription factor subunit, Interferon-stimulated gene factor 3 gamma, IRF 9, IRF-9

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Product Information

85160-2-PBS targets IRF9 in WB, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: IRF9 fusion protein Ag5365
• Full Name: IRF 9
• Calculated Molecular Weight: 393 aa, 44 kDa
• Observed Molecular Weight: 44-48 kDa
• GenBank Accession Number: BC035716
• Gene Symbol: IRF9
• Gene ID (NCBI): 10379
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: Q00978
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

IRF9 also named ISGF3 is a transcription regulatory factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of IFN stimulated genes, which drive the cell in an antiviral state.