Filter: AllIHC

IHC staining of human pancreas cancer using 21703-1-AP
Immunohistochemical analysis of paraffin-embedded human pancreas cancer tissue slide using 21703-1-AP (Integrin beta-6 Antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).
IHC staining of human pancreas cancer using 21703-1-AP
Immunohistochemical analysis of paraffin-embedded human pancreas cancer tissue slide using 21703-1-AP (Integrin beta-6 Antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).
IHC staining of human ovary tumor using 21703-1-AP
Immunohistochemical analysis of paraffin-embedded human ovary tumor tissue slide using 21703-1-AP (Integrin Beta 6 antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).
IHC staining of human ovary tumor using 21703-1-AP
Immunohistochemical analysis of paraffin-embedded human ovary tumor tissue slide using 21703-1-AP (Integrin Beta 6 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).
IHC staining of human ovary tumor using 21703-1-AP
Immunohistochemical analysis of paraffin-embedded human ovary tumor tissue slide using 21703-1-AP (Integrin Beta 6 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).
IHC staining of human ovary tumor using 21703-1-AP
Immunohistochemical analysis of paraffin-embedded human ovary tumor tissue slide using 21703-1-AP (Integrin Beta 6 antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

Integrin Beta 6 Polyclonal antibody

Integrin Beta 6 Polyclonal Antibody for IHC, ELISA

Cat No. 21703-1-AP

Review Product

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

IHC, ELISA

Synonyms

ITGB6, Integrin beta-6, integrin, beta 6

Formulation: PBS, Azide, Glycerol

PBS, Azide, Glycerol

Conjugate: Unconjugated

Unconjugated

Size/Concentration:

-/ -

Freight/Packing: -

Quantity

- +

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Overview

Tested Applications
Product Information
Protocols

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MSDS SDS

Tested Applications

Positive IHC detected in

human ovary tumor tissue, human pancreas cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

Application	Dilution
Immunohistochemistry (IHC)	IHC : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

21703-1-AP targets Integrin Beta 6 in IHC, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity	human, mouse, rat
Host / Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	CatNo: Ag16319 Product name: Recombinant human Integrin beta-6 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 139-434 aa of BC121178 Sequence: MDLSASMDDDLNTIKELGSRLSKEMSKLTSNFRLGFGSFVEKPVSPFVKTTPEEIANPCSSIPYFCLPTFGFKHILPLTNDAERFNEIVKNQKISANIDTPEGGFDAIMQAAVCKEKIGWRNDSLHLLVFVSDADSHFGMDSKLAGIVIPNDGLCHLDSKNEYSMSTVLEYPTIGQLIDKLVQNNVLLIFAVTQEQVHLYENYAKLIPGATVGLLQKDSGNILQLIISAYEELRSEVELEVLGDTEGLNLSFTAICNNGTLFQHQKKCSHMKVGDTASFSVTVNIPHCERRSRHII Predict reactive species
Full Name	integrin, beta 6
Calculated Molecular Weight	788 aa, 86 kDa
GenBank Accession Number	BC121178
Gene Symbol	Integrin beta 6
Gene ID (NCBI)	3694
RRID	AB_2878906
Conjugate	Unconjugated
Form	Liquid
Purification Method	Antigen affinity purification
UNIPROT ID	P18564
Storage Buffer	PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions	Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

ITGB6 belongs to the integrin beta chain family. ITGB6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of integrin alpha-V/beta-6 via clathrin-mediated endocytosis promotes carcinoma cell invasion.