ITLN2 Polyclonal antibody, PBS Only

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• ITLN2 Polyclonal antibody, PBS Only (18815-1-PBS)

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  WB analysis using 18815-1-AP (same clone as 18815-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 18815-1-AP (ITLN2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 18815-1-PBS in a different storage buffer formulation.

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  IHC staining of human colon cancer using 18815-1-AP (same clone as 18815-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon cancer slide using 18815-1-AP (ITLN2 antibody) at dilution of 1:200 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 18815-1-PBS in a different storage buffer formulation.

ITLN2 Polyclonal Antibody for WB, IHC, Indirect ELISA

Cat No. 18815-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

mouse

Applications

WB, IHC, Indirect ELISA

Synonyms

Intelectin-2, intelectin 2, HL2, HL 2, Endothelial lectin HL-2

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Product Information

18815-1-PBS targets ITLN2 in WB, IHC, Indirect ELISA applications and shows reactivity with mouse samples.

• Tested Reactivity: mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  Peptide

• Full Name: intelectin 2
• Calculated Molecular Weight: 36 kDa
• Observed Molecular Weight: 36 kDa
• GenBank Accession Number: BC143341
• Gene Symbol: ITLN2
• Gene ID (NCBI): 142683
• RRID: AB_3669302
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q8WWU7
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

ITLN2 also named as UNQ2789 and PRO7179, may play a role in the defense system against pathogens. Intelectins (intestinal lectins) are highly conserved across chordate evolution and have been implicated in various human diseases, including Crohn's disease (CD). The human genome encodes two intelectin genes, intelectin-1 (ITLN1) and intelectin-2 (ITLN2). It is reproted that human ITLN2 is expressed in Paneth cells, where it localizes to secretory granules, and establish that ITLN2 is a highly abundant multimeric protein secreted into the lumen of the small intestine (PMID: 35182405). The calculated molecular weight of ITLN2 is 36 kDa.