Product Information
87737-1-PBS targets Pig IgD in WB, Indirect ELISA applications and shows reactivity with pig samples.
| Tested Reactivity | pig |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen |
CatNo: Eg7410 Product name: Recombinant Pig IgD protein (His Tag) Source: mammalian cells-derived, V37 Tag: C-6*His Domain: 102-400 aa of / Sequence: ISGPASRQLPAPAGTPGPTLSTVSTKALTTPRIPVRSTVRGQPGAQTQEPPEGPRGACQNHTRPPSVYLLLPPLQGLWLRAEATFTCLAVGQDLQEARLSWAVAEEPQGGRMEEGPTEHTNGSWSLSSRLALPRSSWAAGAPVTCRLSGPGLRSLVTAEARREHAALAPSNLAVRVLTAPGPLAFTKAASWLLCEVSSFSPLDILLTWLEGQQEVDPSWFATARPAAQPGNPTFRTWSVLRVPASPGHQDATYTCVVGHEASRTLLNASWRLDTGPLLIQQRLGAEWKASKRAPASPEA Predict reactive species |
| Full Name | Pig IgD |
| Calculated Molecular Weight | 43 kDa |
| Observed Molecular Weight | 75 kDa and 25 kDa |
| GenBank Accession Number | / |
| Gene Symbol | |
| Gene ID (NCBI) | / |
| RRID | AB_3745724 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | K7ZRJ8 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
Immunoglobulin D (IgD) is an antibody class primarily functioning as a membrane-bound receptor on the surface of naïve B cells. Comprising less than 1% of serum immunoglobulins, IgD exists mainly in a transmembrane form that co-expresses with IgM on mature B lymphocytes. It plays a crucial role in B cell activation, survival, and immune surveillance by sensing environmental antigens and regulating humoral immune responses. Recent studies reveal IgD's involvement in mucosal immunity and its ability to bind to basophils and mast cells, triggering antimicrobial defense. Structurally, IgD features an extended hinge region, making it susceptible to proteolytic cleavage. Despite being discovered in 1965, IgD's precise functions remain an active area of immunological research. The immunogen for this antibody is Eg7410, and the immunogen sequence targets the Fc region of porcine IgD.
