Jagged1 Polyclonal antibody

Jagged1 Polyclonal Antibody for ELISA
Cat No. 17791-1-AP

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

ELISA

AGS, AHD, AWS, CD339, HJ1, JAG1, jagged 1 (Alagille syndrome), Jagged1, JAGL1, Protein jagged 1

Formulation:  PBS and Azide
PBS and Azide
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

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Product Information

17791-1-AP targets Jagged1 in ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Jagged1 fusion protein Ag11891 Predict reactive species
Full Name jagged 1 (Alagille syndrome)
Calculated Molecular Weight 1218 aa, 134 kDa
GenBank Accession NumberBC098393
Gene Symbol Jagged1
Gene ID (NCBI) 182
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP78504
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

JAG1, also named as JAGL1, CD339 and Jagged1, is a ligand for multiple Notch receptors and involved in the mediation of Notch signaling. It may be involved in cell-fate decisions during hematopoiesis. JAG1 seems to be involved in early and late stages of mammalian cardiovascular development. It inhibits myoblast differentiation. JAG1 enhances fibroblast growth factor-induced angiogenesis. JAG1 signalling through notch 1 has also been shown to play a role in hematopoiesis.

Publications

SpeciesApplicationTitle
humanWB,IHC

Front Immunol

Significance of NotchScore and JAG1 in predicting prognosis and immune response of low-grade glioma

Authors - Bo Shi
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