Product Information
13551-1-AP targets JAK3 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | human, mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag4298 Product name: Recombinant human JAK3 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-350 aa of BC028068 Sequence: MAPPSEETPLIPQRSCSLLSTEAGALHVLLPARGPGPPQRLSFSFGDHLAEDLCVQAAKASGILPVYHSLFALATEDLSCWFPPSHIFSVEDASTQVLLYRIRFYFPNWFGLEKCHRFGLRKDLASAILDLPVLEHLFAQHRSDLVSGRLPVGLSLKEQGECLSLAVLDLARMAREQAQRPGELLKTVSYKACLPPSLRDLIQGLSFVTRRRIRRTVRRALRRVAACQADRHSLMAKYIMDLERLDPAGAAETFHVGLPGALGGHDGLGLLRVAGDGGIAWTQGEQEVLQPFCDFPEIVDISIKQAPRVGPAGEHRLVTVTRTDNQILEAEFPGLPEALSFVALVDGYFR Predict reactive species |
| Full Name | Janus kinase 3 (a protein tyrosine kinase, leukocyte) |
| Calculated Molecular Weight | 1124 aa, 125 kDa |
| GenBank Accession Number | BC028068 |
| Gene Symbol | JAK3 |
| Gene ID (NCBI) | 3718 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | P52333 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Publications
What published studies show
The JAK3 Polyclonal antibody (Cat# 13551-1-AP) has 2 total citations. One appears in Journal of Pharmaceutical Analysis (IF 11.2), studying ginsenoside Rk3's modulation of gut microbiota and immune response against colorectal tumorigenesis in mice. The other is in BMC Complementary Medicine and Therapies (IF 4.4), investigating active components and molecular mechanisms of Gandi capsule for treating diabetic nephropathy in humans. Both citations used WB application, spanning research fields of oncology/immunology and metabolic disease/pharmacology.
| Species | Application | Title |
|---|---|---|
J Pharm Anal Ginsenoside Rk3 modulates gut microbiota and regulates immune response of group 3 innate lymphoid cells to against colorectal tumorigenesis | ||
BMC Complement Med Ther Revealing active components, action targets and molecular mechanism of Gandi capsule for treating diabetic nephropathy based on network pharmacology strategy. |
