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KALRN Polyclonal antibody, PBS Only

KALRN Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA

Cat No. 19740-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, IF/ICC, Indirect ELISA

Formulation:  PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

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Product Information

19740-1-PBS targets KALRN in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen

Peptide

Predict reactive species
Full Name kalirin, RhoGEF kinase
Calculated Molecular Weight 340 kDa
Observed Molecular Weight 200 kDa
GenBank Accession NumberNM_007064
Gene Symbol KALRN
Gene ID (NCBI) 8997
RRIDAB_10638319
Conjugate Unconjugated
FormLiquid
Purification MethodAntigen affinity purification
UNIPROT IDO60229
Storage Buffer PBS only, pH 7.3.
Storage ConditionsStore at -80°C.

Background Information

KALRN, also named as DUET, DUO, HAPIP and TRAD, belongs to the protein kinase superfamily and CAMK Ser/Thr protein kinase family. KALRN promotes the exchange of GDP by GTP. KALRN activates specific Rho GTPase family members, thereby inducing various signaling mechanisms that regulate neuronal shape, growth, and plasticity, through their effects on the actin cytoskeleton. KALRN induces lamellipodia independent of its GEF activity. The antibody can recognize isoform1 and isoform2 of KALRN.

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