KCNIP2 Polyclonal antibody

KCNIP2 Polyclonal Antibody for ELISA
Cat No. 20192-1-AP

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, ELISA

A-type potassium channel modulatory protein 2, Cardiac voltage-gated potassium channel modulatory subunit, KChIP2, Kv channel-interacting protein 2, Potassium channel-interacting protein 2

Formulation:  PBS and Azide
PBS and Azide
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

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Published Applications

WBSee 1 publications below

Product Information

20192-1-AP targets KCNIP2 in WB, ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Cited Reactivitymouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen

CatNo: Ag14111

Product name: Recombinant human KCNIP2 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-70 aa of BC034685

Sequence: MRGQGRKESLSDSRDLDGSYDQLTGHPPGPTKKALKQRFLKLLPCCGPQALPSVSENSVDDEFELSTVCH

Predict reactive species
Full Name Kv channel interacting protein 2
Calculated Molecular Weight 270 aa, 31 kDa
Observed Molecular Weight 29-31 kDa
GenBank Accession NumberBC034685
Gene Symbol KCNIP2
Gene ID (NCBI) 30819
RRIDAB_2878655
Conjugate Unconjugated
FormLiquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9NS61
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

KCNIP2 is a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belongs to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified from this gene.This antibody can recognize 31 kDa and 29 kDa isoforms.

Publications

SpeciesApplicationTitle
mouseWB

J Cell Physiol

Involvement of TRPV4 in changes in rapidly inactivating potassium channels in the early stage of pilocarpine-induced status epilepticus in mice.

Authors - Weixing Xu
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