KCNK5 Polyclonal antibody

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• KCNK5 Polyclonal antibody (14136-1-AP)

KCNK5 Polyclonal Antibody for WB, ELISA

Cat No. 14136-1-AP Copied!

Publications (1)

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Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Synonyms

Acid-sensitive potassium channel protein TASK-2, K2p5.1, TASK 2, TASK2, TWIK-related acid-sensitive K(+) channel 2

• 

  WB analysis using 14136-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 14136-1-AP (KCNK5 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy

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Tested Applications

• Positive WB detected in: HEK-293 cells, HepG2 cells, L02 cells, PC-3 cells

Recommended dilution

• Western Blot (WB): WB : 1:500-1:2000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

14136-1-AP targets KCNK5 in WB, ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Cited Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag5355

  Product name: Recombinant human KCNK5 protein

  Source: e coli.-derived, PET28a

  Tag: 6*His

  Domain: 244-499 aa of BC060793

  Sequence: WKVSMFVEVHKAIKKRRRRRKESFESSPHSRKALQVKGSTASKDVNIFSFLSKKEETYNDLIKQIGKKAMKTSGGGETGPGPGLGPQGGGLPALPPSLVPLVVYSKNRVPTLEEVSQTLRSKGHVSRSPDEEAVARAPEDSSPAPEVFMNQLDRISEECEPWDAQDYHPLIFQDASITFVNTEAGLSDEETSKSSLEDNLAGEESPQQGAEAKAPLNMGEFPSSSESTFTSTESELSVPYEQLMNEYNKANSPKGT

• Full Name: potassium channel, subfamily K, member 5
• Calculated Molecular Weight: 499 aa, 55 kDa
• Observed Molecular Weight: 70 kDa, 55 kDa
• GenBank Accession Number: BC060793
• Gene Symbol: KCNK5
• Gene ID (NCBI): 8645
• RRID: AB_2280811
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: O95279
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Potassium channel subfamily K member 5 (KCNK5, also termed TASK2) is a potassium channel mediating voltage-dependent outward-rectifying currents in response to membrane depolarization. Its voltage sensing is coupled to the potassium electrochemical gradient via an "ion flux gating" mechanism, in which gate opening is triggered by outward rather than inward ion movement (PMID: 26919430; 36063992; 9812978). Immunoblotting analysis of KCNK5 detects two protein bands at 55 kDa and 70 kDa, representing the monomeric and glycosylated forms of the KCNK5 potassium channel, respectively (PMID: 24285684; 26140335).

Publications

What published studies show

The antibody Cat# 14136-1-AP has 1 total citation. It appears in Scientific Reports (Sci Rep, IF 4.9), published November 2025. The associated research field is oncology, specifically clear cell renal cell carcinoma (ccRCC), where KCNK5 was identified as a novel prognostic biomarker linked to immune infiltration. The application used was Western Blot (WB) in human samples.

Automatically generated from the 1 publication citations by Able AI.

• Human
• Mouse
• Rat
• Monkey
• Pig

Species	Application	Title
human	WB	Sci Rep; A SWI/SNF complex-related genes signature predicts prognosis and immune infiltration in ccRCC with KCNK5 as a novel biomarker.; Authors - Kai Xu