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KCNN1 Polyclonal antibody

KCNN1 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

hSK1, KCa2.1, KCNN1, SK, SK1, SKCa 1, SKCA1

Formulation:  PBS, Azide, Glycerol
PBS, Azide, Glycerol
Conjugate:  Unconjugated
Unconjugated
Size/Concentration: 
SKU: 

-/ -

Freight/Packing: -

Quantity

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What's the best dilution for KCNN1 in ?

Tested Applications

Positive WB detected inmouse brain tissue

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:4000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

17929-1-AP targets KCNN1 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivitymouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen

CatNo: Ag12357

Product name: Recombinant human KCNN1 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 366-543 aa of BC075037

Sequence: ARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKHTRLVKKPDQARVRKHQRKFLQAIHQAQKLRSVKIEQGKLNDQANTLTDLAKTQTVMYDLVSELHAQHEELEARLATLESRLDALGASLQALPGLIAQAIRPPPPPLPPRPGPGPQDQAARSSPCRWTPVAPSDCG

Predict reactive species
Full Name potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1
Calculated Molecular Weight 543 aa, 60 kDa
Observed Molecular Weight 70 kDa
GenBank Accession NumberBC075037
Gene Symbol KCNN1
Gene ID (NCBI) 3780
RRIDAB_2131511
Conjugate Unconjugated
FormLiquid
Purification MethodAntigen affinity purification
UNIPROT IDQ92952
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Protocols

Product Specific Protocols
WB protocol for KCNN1 antibody 17929-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

What published studies show

The KCNN1 Polyclonal antibody (Cat# 17929-1-AP) has 2 total citations. These appear in International Journal of Molecular Sciences and Proceedings of the National Academy of Sciences of the United States of America. The research fields include oxidative stress and Nrf2/MAPK signaling in alcohol-induced liver injury, and neuronal α-synuclein pathology in Parkinson's disease models.

SpeciesApplicationTitle
mouseWB

Int J Mol Sci

Kadsura coccinea Roots Ameliorated Alcohol-Induced Liver Injury by Modulating Oxidative Stress Through the Regulation of the Nrf2/MAPK Signaling Pathway.

Authors - Yashi Wang

Proc Natl Acad Sci U S A

Neuronal overexpression of Kcnn1 in A53T α-synuclein mice suppresses phospho-serine 129 α-synuclein formation and doubles survival time.

Authors - Maria Nagy
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