Tested Applications
| Positive WB detected in | mouse brain tissue |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:1000-1:4000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
17929-1-AP targets KCNN1 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag12357 Product name: Recombinant human KCNN1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 366-543 aa of BC075037 Sequence: ARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKHTRLVKKPDQARVRKHQRKFLQAIHQAQKLRSVKIEQGKLNDQANTLTDLAKTQTVMYDLVSELHAQHEELEARLATLESRLDALGASLQALPGLIAQAIRPPPPPLPPRPGPGPQDQAARSSPCRWTPVAPSDCG Predict reactive species |
| Full Name | potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1 |
| Calculated Molecular Weight | 543 aa, 60 kDa |
| Observed Molecular Weight | 70 kDa |
| GenBank Accession Number | BC075037 |
| Gene Symbol | KCNN1 |
| Gene ID (NCBI) | 3780 |
| RRID | AB_2131511 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q92952 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for KCNN1 antibody 17929-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
What published studies show
The KCNN1 Polyclonal antibody (Cat# 17929-1-AP) has 2 total citations. These appear in International Journal of Molecular Sciences and Proceedings of the National Academy of Sciences of the United States of America. The research fields include oxidative stress and Nrf2/MAPK signaling in alcohol-induced liver injury, and neuronal α-synuclein pathology in Parkinson's disease models.
| Species | Application | Title |
|---|---|---|
Int J Mol Sci Kadsura coccinea Roots Ameliorated Alcohol-Induced Liver Injury by Modulating Oxidative Stress Through the Regulation of the Nrf2/MAPK Signaling Pathway. | ||
Proc Natl Acad Sci U S A Neuronal overexpression of Kcnn1 in A53T α-synuclein mice suppresses phospho-serine 129 α-synuclein formation and doubles survival time. |

