KIAA2013 Recombinant monoclonal antibody

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• KIAA2013 Recombinant monoclonal antibody (87068-4-RR)

• 

  WB analysis using 87068-4-RR

  Various lysates were subjected to SDS PAGE followed by western blot with 87068-4-RR (KIAA2013 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours.

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  Affinity of 87068-4-RR

  Biolayer interferometry (BLl) kinetic assays of 87068-4-RR against Human KIAA2013 were performed. The affinity constant is below 1 pM.

KIAA2013 Uni-rAb^® Recombinant Antibody for WB, ELISA

Cat No. 87068-4-RR

Clone No.252306A2

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Synonyms

K2013, Uncharacterized protein KIAA2013

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Tested Applications

• Positive WB detected in: LNCaP cells

Recommended dilution

• Western Blot (WB): WB : 1:5000-1:50000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

87068-4-RR targets KIAA2013 in WB, ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  CatNo: Ag27379

  Product name: Recombinant human KIAA2013 protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 52-393 aa of BC035033

  Sequence: WSRGEPGAAEPSACLEAATRAWRGLRERGEVVPLGPGVPALVANGFLALDVAANRLWVTPGEREPAVAPDFVPFVQLRPLSALAEAGEAVLLLREGLLRRVRCLQLGSPGPGPVAAGPGPASVSGLAAGSGRDCVLLQEDFLAHRGRPHVYLQRIQLNNPTERVAALQTVGPTAGPAPKAFTSTLEKVGDHQFLLYSGRSPPTPTGLVHLVVVAAKKLVNRLQVAPKTQLDETVLWVVHVSGPINPQVLKSKAAKELKALQDLARKEMLELLDMPAAELLQDHQLLWAQLFSPGVEMKKITDTHTPSGLTVNLTLYYMLSCSPAPLLSPSLSHRERDQMEST

• Full Name: KIAA2013
• Observed Molecular Weight: 65 kDa
• GenBank Accession Number: BC035033
• Gene Symbol: KIAA2013
• Gene ID (NCBI): 90231
• RRID: AB_3745313
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: Q8IYS2
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

KIAA2013, also known as Q8IYS2 or MGC33867, is a single-pass transmembrane protein encoded by the KIAA2013 gene in humans. KIAA2013 has been found to play a role in the Endocannabinoid system. This system is made up of cannabinoid receptors 1 and 2 (CB1 and CB2) as well as the various ligands and enzymes that interact. The protein KIAA2013 has been found to be expressed within CB2 expressing cells. Both cannabinoid receptors are labeled as class A G-Protein Coupled Receptors, and CB2 is highly expressed within the human spleen and leukocytes. CB2, and by extension KIAA2013, are therefore targets of interest for therapeutic studies looking into diseases such as inflammatory bowel disease and rheumatoid arthritis(PMID:31616248 34752341).