|Positive WB detected in||HepG2 cells, Jurkat cells, pig liver tissue, human placenta tissue|
|Positive IHC detected in||human liver tissue, human lung cancer tissue|
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
|Western Blot (WB)||WB : 1:1000-1:4000|
|Immunohistochemistry (IHC)||IHC : 1:50-1:500|
|Sample-dependent, check data in validation data gallery|
27823-1-AP targets LAMP2 in WB, IHC, IF, ELISA applications and shows reactivity with Human, Pig samples.
|Tested Reactivity||Human, Pig|
|Cited Reactivity||human, pig|
|Host / Isotype||Rabbit / IgG|
|Immunogen||LAMP2 fusion protein Ag27183|
|Full Name||lysosomal-associated membrane protein 2|
|Calculated molecular weight||45 kDa|
|Observed molecular weight||120 kDa|
|GenBank accession number||BC002965|
|Gene ID (NCBI)||3920|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.|
Lysosomal-associated membrane protein 2 (LAMP2, synonyms: LAMPB, CD107b) is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. LAMP2 may plays a role in tumor cell metastasis. It may also functions in the protection, maintenance, and adhesion of the lysosome. Prior to posttranslational modification, LAMP2 is a ~45 kDa polypeptide. Mature, functional LAMP2 is extensively glycosylated with a variety of different N linked and O linked oligosaccharides.
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