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LBP Recombinant monoclonal antibody, PBS Only (83427-1-PBS)

LBP Recombinant monoclonal antibody, PBS Only

Name: LBP Recombinant monoclonal antibody, PBS Only, 100ug
Brand: Proteintech
SKU: 83427-1-PBS-100UG

LBP Uni-rAb^® Recombinant Antibody for ELISA, WB

Cat No. 83427-1-PBS

Clone No. 230524G10

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Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

ELISA, WB

Synonyms

Lipopolysaccharide-binding protein, 230524G10

Formulation: PBS Only

PBS, Azide, Glycerol

PBS Only

Conjugate: Unconjugated

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Filter: AllWBAffinity

WB analysis of A431 using 83427-1-RR (same clone as 83427-1-PBS)
A431 cells were subjected to SDS PAGE followed by western blot with 83427-1-RR (LBP antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83427-1-PBS in a different storage buffer formulation.
This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
Affinity and Kinetic Characterization of 83427-1-RR
Biolayer interferometry (BLl) kinetic assays of 83427-1-RR against Human LBP were performed. The affinity constant is 27.1 nM.
This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy

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Overview

Tested Applications
Product Information

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MSDS SDS

Product Information

83427-1-PBS targets LBP in ELISA, WB applications and shows reactivity with human samples.

Tested Reactivity	human
Host / Isotype	Rabbit / IgG
Class	Recombinant
Type	Antibody
Immunogen	Fusion Protein Predict reactive species
Full Name	lipopolysaccharide binding protein
Calculated Molecular Weight	53KD
GenBank Accession Number	NM_004139.4
Gene Symbol	LBP
Gene ID (NCBI)	3929
RRID	AB_3671074
Conjugate	Unconjugated
Form	Liquid
Purification Method	Protein A purification
UNIPROT ID	P18428
Storage Buffer	PBS only, pH 7.3.
Storage Conditions	Store at -80°C.

Background Information

LBP (lipopolysaccharide-binding protein) is an acute-phase protein, predominantly synthesized by hepatocytes. It is present in normal serum at concentrations of 5 to 10 μg/ml, rising up to 200 μg/ml 24 h after induction of an acute-phase response. LBP binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria, and acts as an affinity enhancer for CD14, facilitating its association with LPS. (PMID: 9665271; 11598069)