LEO1 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 12281-1-AP

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Freight/Packing

Con: 61 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
mouse heart tissue, HeLa cells, HL-60 cells, human placenta tissue, Jurkat cells, mouse brain tissue, mouse heart tissue, mouse skeletal muscle tissue

Positive IHC detected in:
human colon tissue

Positive IF detected in:
Hela cells

Recommended dilution:
WB : 1:500-1:2400
IHC : 1:20-1:200
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)

Calculated molecular weight:
666aa,75 kDa

Observed molecular weight:
105 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
LEO1

Synonyms
LEO1, RDL
Background

LEO1, also named as RNA polymerase-associated protein LEO1, is a 666 amino acid protein, which belongs to the LEO1 family. LEO1 is a component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II and is implicated in regulation of development and maintenance of embryonic stem cell pluripotency. The calculated molecular weight of LEO1 is 75 kDa, but the modified LEO1 protein is about 105 kDa (PMID: 15632063).


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