Lamin B1 Antibody 22 Publications

Mouse Monoclonal| Catalog number: 66095-1-Ig |CloneNo.: 3C10G12

Featured Product KD/KO validated

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Freight/Packing

Con: 161 μg/150 μl

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Species specificity:
human, mouse, rat, Rabbit

Positive WB detected in:
HeLa cells, HepG2 cells, multi-cells/tissue

Positive IP detected in:
HeLa cells

Positive IHC detected in:
human pancreas cancer tissue, human breast cancer tissue

Positive IF detected in:
HepG2 cells

Positive FC detected in:
HeLa cells

ApplicationNote:
I recently tried the mouse (antibody 66095-1-Ig) and it works great. (by Stellrecht, Christine)

Recommended dilution:
WB : 1:5000-1:50000
IP : 0.5-4.0 ug for IP and 1:5000-1:50000 for WB
IHC : 1:500-1:2000
IF : 1:50-1:500

Product Information


Source:
Mouse

Purification method:
Protein G purification

Isotype:
IgG1

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
lamin B1

Calculated molecular weight:
66 kDa

Observed molecular weight:
66-70 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
LMNB1

Synonyms
ADLD, lamin B1, LMN, LMN2, LMNB, LMNB1
Background

Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. This protein is not suitable for samples where the nuclear envelope has been removed.


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