LOXL2 Polyclonal antibody

LOXL2 Polyclonal Antibody for IHC, WB, ELISA

Host / Isotype

Rabbit / IgG







Cat no : 15232-1-AP


LOR2, LOXL2, Lysyl oxidase homolog 2, lysyl oxidase like 2, Lysyl oxidase like protein 2, WS9 14

Tested Applications

Positive WB detected inA431 cells, MDA-MB-453s cells, HeLa cells
Positive IHC detected inhuman breast cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

Western Blot (WB)WB : 1:500-1:3000
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Published Applications

WBSee 1 publications below

Product Information

15232-1-AP targets LOXL2 in WB, IHC, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Cited Reactivityhuman
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen LOXL2 fusion protein Ag7083
Full Name lysyl oxidase-like 2
Calculated Molecular Weight 774 aa, 87 kDa
Observed Molecular Weight68 kDa. 100 kDa
GenBank Accession NumberBC000594
Gene Symbol LOXL2
Gene ID (NCBI) 4017
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

LOXL2, also named as WS9-14, belongs to an amine oxidase family whose members have been implicated in crosslink formation in stromal collagens and elastin, cell motility, and tumor development and progression. LOXL2 activity might be a crucial modulator of Snail, providing an additional control mechanism of EMT and tumor progression. Increased LOXL2 expression in colon and esophageal cancer may contribute to tumor progression.


Product Specific Protocols
WB protocol for LOXL2 antibody 15232-1-APDownload protocol
IHC protocol for LOXL2 antibody 15232-1-APDownload protocol
IF protocol for LOXL2 antibody 15232-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols



J Cancer

Dihydroartemisinin Potentiates VEGFR-TKIs Antitumorigenic Effect on Osteosarcoma by Regulating Loxl2/VEGFA Expression and Lipid Metabolism Pathway

Authors - Xiaomin Ding