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EDG2/LPA1 Recombinant monoclonal antibody

EDG2/LPA1 Uni-rAb® Recombinant Antibody for WB, ELISA

Cat No. 86655-2-RR
Clone No.251542A6

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, ELISA

LPAR1, edg 2, EDG2, Gpcr26, GPR26

Formulation:  PBS, Azide, Glycerol
PBS, Azide, Glycerol
PBS Only
Conjugate:  Unconjugated
Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

Please visit your regions distributor:


Tested Applications

Positive WB detected inHeLa cells, A2780 cells, MG-63 cells, HuH-7 cells, NIH/3T3 cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:6000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Published Applications

WBSee 1 publications below

Product Information

86655-2-RR targets EDG2/LPA1 in WB, ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Cited Reactivityhuman
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen

Peptide

Predict reactive species
Full Name lysophosphatidic acid receptor 1
Calculated Molecular Weight 364 aa, 41 kDa
Observed Molecular Weight50 kDa
GenBank Accession NumberBC030615
Gene Symbol EDG2
Gene ID (NCBI) 1902
RRIDAB_3745034
Conjugate Unconjugated
FormLiquid
Purification MethodProtein A purification
UNIPROT IDQ92633
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

EDG2 (also known as LPA1) is a G-protein coupled receptor for lysophosphatidic acid (LPA), a potent motility inducing factor, which is a major component of serum (PMID: 19415462). EDG2 is widely expressed in normal tissue during growth and development. In the context of cancer, several studies have suggested that EDG2 expression in tumors is often similar to that shown in normal tissue (PMID: 17496233).

Protocols

Product Specific Protocols
WB protocol for EDG2/LPA1 antibody 86655-2-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB

Front Immunol

Identify GDPD3 as a key regulator of epithelial-mesenchymal transition and prostate adenocarcinoma progression via the LPA/LPAR1/AKT axis: transcriptomic and experimental study.

Authors - Lin Hao
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