Product Information
16291-1-AP targets LYPLA2 in ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag9452 Product name: Recombinant human LYPLA2 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-231 aa of BC017193 Sequence: MCGNTMSVPLLTDAATVSGAERETAAVIFLHGLGDTGHSWADALSTIRLPHVKYICPHAPRIPVTLNMKMVMPSWFDLMGLSPDAPEDEAGIKKAAENIKALIEHEMKNGIPANRIVLGGFSQGGALSLYTALTCPHPLAGIVALSCWLPLHRAFPQAANGSAKDLAILQCHGELDPMVPVRFGALTAEKLRSVVTPARVQFKTYPGVMHSSCPQEMAAVKEFLEKLLPPV Predict reactive species |
| Full Name | lysophospholipase II |
| Calculated Molecular Weight | 231 aa, 25 kDa |
| GenBank Accession Number | BC017193 |
| Gene Symbol | LYPLA2 |
| Gene ID (NCBI) | 11313 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | O95372 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
LYPLA2(lysophospholipase II) is also named as APT2(acyl-protein thioesterase 2) and belongs to the AB hydrolase 2 family. It may hydrolyze fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Two cytosolic acyl thioesterases(APT1 and APT2, genes LYPLA1 and LYPLA2, respectively) have been identified as palmitoyl thioesterases that depalmitoylate cytosolic cysteine residues of proteins(PMID:22399288).
