ASK1 Antibody 2 Publications

Rabbit Polyclonal| Catalog number: 14385-1-AP

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Freight/Packing

Con: 20 μg/150 μl

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Tested Applications

Applications:
ELISA, WB
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Species specificity:
human, mouse, rat, monkey

Recommended dilution:

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
mitogen-activated protein kinase kinase kinase 5

Calculated molecular weight:
155 kDa

Observed molecular weight:

GenBank accession number:

Gene ID (NCBI):

Gene symbol
MAP3K5

Synonyms
ASK 1, ASK1, MAP3K5, MAPK/ERK kinase kinase 5, MAPKKK5, MEK kinase 5, MEKK 5, MEKK5
Background

ASK1(Apoptosis signal-regulating kinase 1) is also named as MAP3K5, MAPKKK5, MEKK5 and belongs to the MAP kinase kinase kinase subfamily. It is an evolutionarily conserved mitogen activated protein 3-kinase that activates both Jnk and p38 mitogen-activated protein kinases. ASK1 is is activated in response to various cytotoxic stresses including TNF, Fas and reactive oxygen species (ROS) such as H2O2, and activates c-Jun NH 2-terminal kinase (JNK) and p38.


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