MAP4K2 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 55244-1-AP

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Freight/Packing

Con: 70 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
mouse brain tissue, human brain tissue, Raji cells

Recommended dilution:
WB : 1:500-1:1000

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
mitogen-activated protein kinase kinase kinase kinase 2

Calculated molecular weight:
92 kDa

Observed molecular weight:
85-91kd,58kd

GenBank accession number:

Gene ID (NCBI):

Gene symbol
MAP4K2

Synonyms
MAP4K2, MEK kinase kinase 2, Germinal center kinase, GCK, GC kinase
Background

MAP4K2,also named as GCK and RAB8IP, belongs to the protein kinase superfamily, STE Ser/Thr protein kinase family and STE20 subfamily. It enhances MAP3K1 oligomerization, which may relieve amino-terminal mediated MAP3K1 autoinhibition and lead to activation following autophosphorylation. MAP4K2 may play a role in the regulation of vesicle targeting or fusion. This antibody is specific to MAP4K2.


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