MCM10 Recombinant monoclonal antibody, PBS Only

• 

  WB analysis using 86103-1-RR (same clone as 86103-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 86103-1-RR (MCM10 antibody) at dilution of 1:30000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86103-1-PBS in a different storage buffer formulation.

MCM10 Uni-rAb^® Recombinant Antibody for WB, Indirect ELISA

Cat No. 86103-1-PBS

Clone No.250423A12

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Synonyms

CNA43, DNA43, HsMCM10, PRO2249, Protein MCM10 homolog

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Product Information

86103-1-PBS targets MCM10 in WB, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  CatNo: Ag2899

  Product name: Recombinant human MCM10 protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 259-611 aa of BC009108

  Sequence: MDLPTCGARNLKQHLAKASASGIMGSPKPAIKSISASALLKQQKQRMLEMRRRKSEEIQKRFLQSSSEVESPAVPSSSRQPPAQPPRTGSEFPRLEGAPATMTPKLGRGVLEGDDVLFYDESPPPRPKLSALAEAKKLAAITKLRAKGQVLTKTNPNSIKKKQKDPQDILEVKERVEKNTMFSSQAEDELEPARKKRREQLAYLESEEFQKILKAKSKHTGILKEAEAEMQERYFEPLVKKEQMEEKMRNIREVKCRVVTCKTCAYTHFKLLETCVSEQHEYHWHDGVKRFFKCPCGNRSISLDRLPNKHCSNCGLYKWERDGMLKEKTGPKIGGETLLPRGEEHAKFLNSLK

• Full Name: minichromosome maintenance complex component 10
• Calculated Molecular Weight: 874 aa, 97 kDa
• Observed Molecular Weight: 97-105 kDa
• GenBank Accession Number: BC009108
• Gene Symbol: MCM10
• Gene ID (NCBI): 55388
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: Q7L590
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

MCM10, also named as HsMCM10, belongs to the MCM10 family. It acts as a replication initiation factor that brings together the MCM2-7 helicase and the DNA polymerase alpha/primase complex in order to initiate DNA replication. Additionally, it plays a role in preventing DNA damage during replication and is essential for the integrity of the RECQ4-MCM replicative helicase complex. It mediates RECQ4 association with MCM2-7 helicase complex during DNA replication.