M-CSF Polyclonal antibody

M-CSF Polyclonal Antibody for ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human and More (1)

Applications

WB, IF, ELISA, Cell treatment

Conjugate

Unconjugated

Cat no : 14779-1-AP

Synonyms

CSF 1, CSF1, Lanimostim, M CSF, MCSF, M-CSF



Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

14779-1-AP targets M-CSF in WB, IF, ELISA, Cell treatment applications and shows reactivity with human samples.

Tested Reactivity human
Cited Reactivityhuman, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen M-CSF fusion protein Ag6294
Full Name colony stimulating factor 1 (macrophage)
Calculated Molecular Weight 60 kDa
Observed Molecular Weight 70 kDa
GenBank Accession NumberBC021117
Gene Symbol CSF1
Gene ID (NCBI) 1435
RRIDAB_10643241
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Colony stimulating factor-1 (CSF-1) is a homodimeric glycoprotein that humorally regulates the proliferation and differentiation of mononuclear phagocytic cells and locally regulates cells of the female reproductive tract. Alternative splicing of the human CSF-1 mRNA leads to alternative expression of the CSF-1 homodimer as a secreted glycoprotein or as a membrane-spanning molecule with cell surface biological activity. CSF-1 is predominantly secreted as highly sulfated species of 375- and 250-kDa with a smaller amount of a 100-kDa species. The three predominant CSF-1 species were shown to be an 80-kDa homodimer, an 80-kDa/50-kDa heterodimer, and a 50-kDa homodimer. (PMID: 1733926) This antibody could recognieze 60 kDa, 48 kDa, 29 kDa isoforms.

Publications

SpeciesApplicationTitle
mouseWB

J Control Release

Chemoattractants driven and microglia based biomimetic nanoparticle treating TMZ-resistant glioblastoma multiforme.

Authors - Sai Qiao
mouseWB,Cell treatment

J Nanobiotechnology

Biomimetic GBM-targeted drug delivery system boosting ferroptosis for immunotherapy of orthotopic drug-resistant GBM.

Authors - Bao Liu
WB

Biomed Pharmacother

Anti-osteoporotic effects of alisol C 23-acetate via osteoclastogenesis inhibition.

Authors - Xiaokang Jia
humanWB

Int J Biol Sci

Macrophage Colony-stimulating Factor Mediates the Recruitment of Macrophages in Triple negative Breast Cancer.

Authors - Xiaoqing Lu
human,mouseWB

Invest Ophthalmol Vis Sci

CSF1/CSF1R-mediated Crosstalk Between Choroidal Vascular Endothelial Cells and Macrophages Promotes Choroidal Neovascularization.

Authors - Yamei Zhou
mouseWB

Front Physiol

Heat Stress Modulates a Placental Immune Response Associated With Alterations in the Development of the Fetal Intestine and Its Innate Immune System in Late Pregnant Mouse.

Authors - Huiduo Guo