MCTP2 Polyclonal antibody

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• MCTP2 Polyclonal antibody (17578-1-AP)

• 

  WB analysis of mouse liver using 17578-1-AP

  mouse liver tissue were subjected to SDS PAGE followed by western blot with 17578-1-AP (MCTP2 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

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  WB analysis of human placenta using 17578-1-AP

  human placenta tissue were subjected to SDS PAGE followed by western blot with 17578-1-AP (MCTP2 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

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  IHC staining of human brain using 17578-1-AP

  Immunohistochemical analysis of paraffin-embedded human brain using 17578-1-AP (MCTP2 antibody) at dilution of 1:100 (under 10x lens).

• 

  IHC staining of human brain using 17578-1-AP

  Immunohistochemical analysis of paraffin-embedded human brain using 17578-1-AP (MCTP2 antibody) at dilution of 1:100 (under 40x lens).

MCTP2 Polyclonal Antibody for WB, IHC, ELISA

Cat No. 17578-1-AP

Publications(2)

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, ELISA

Synonyms

MCTP2

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Tested Applications

• Positive WB detected in: mouse liver tissue, human placenta tissue
• Positive IHC detected in: human brain tissue; Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

• Western Blot (WB): WB : 1:500-1:2000
• Immunohistochemistry (IHC): IHC : 1:20-1:200

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Published Applications

• KD/KO: See 1 publications below
• WB: See 2 publications below
• IHC: See 2 publications below

Product Information

17578-1-AP targets MCTP2 in WB, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Cited Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag11089

  Product name: Recombinant human MCTP2 protein

  Source: e coli.-derived, PET28a

  Tag: 6*His

  Domain: 4-306 aa of BC025708

  Sequence: LDIEVWGKDNKKHEERLGTCKVDISALPLKQANCLELPLDSCLGALLMLVTLTPCAGVSVSDLCVCPLADLSERKQITQRYCLQNSLKDVKDVGILQVKVLKAADLLAADFSGKSDPFCLLELGNDRLQTHTVYKNLNPEWNKVFTFPIKDIHDVLEVTVFDEDGDKPPDFLGKVAIPLLSIRDGQPNCYVLKNKDLEQAFKGVIYLEMDLIYNPVKASIRTFTPREKRFVEDSRKLSKKILSRDVDRVKRITMAIWNTMQFLKSCFQWESTLRSTIAFAHRKEEPPLSMKCTLFSGDIGPSL

• Full Name: multiple C2 domains, transmembrane 2
• Calculated Molecular Weight: 878 aa, 100 kDa
• Observed Molecular Weight: 100 kDa
• GenBank Accession Number: BC025708
• Gene Symbol: MCTP2
• Gene ID (NCBI): 55784
• RRID: AB_2143118
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q6DN12
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

The MCTP2 (Multiple C2 domains with two transmembrane regions 2) is involved in intercellular signal transduction and synapse function. MCTP2 may be a genetic cause of CoA and related cardiac malformations.

Publications

• Human
• Mouse
• Rat
• Monkey
• Pig

Species	Application	Title
human	WB,IHC	Funct Integr Genomics; Investigating the impact of MCTP2 on immune suppression and drug resistance in glioblastoma.; Authors - Yiguang Chen ; KD Validated
human	WB,IHC	Sci Rep; MCTP2 is a novel biomarker promoting tumor progression and nodal metastasis in oral squamous cell carcinoma; Authors - Yudai Shimojukkoku