MEFV Polyclonal antibody
MEFV Polyclonal Antibody for WB,ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human and More (1)
Applications
WB, IF, FC, ELISA
Conjugate
Unconjugated
Cat no : 24280-1-AP
Synonyms
Validation Data Gallery
Tested Applications
Positive WB detected in | human plasma tissue |
Recommended dilution
Application | Dilution |
---|---|
Western Blot (WB) | WB : 1:500-1:2000 |
Sample-dependent, check data in validation data gallery |
Published Applications
IF | See 1 publications below |
FC | See 1 publications below |
Product Information
The immunogen of 24280-1-AP is MEFV Fusion Protein expressed in E. coli.
Tested Reactivity | human |
Cited Reactivity | human, rat |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | MEFV fusion protein Ag18000 |
Full Name | Mediterranean fever |
Calculated molecular weight | 781 aa, 86 kDa |
Observed molecular weight | 86 kDa |
GenBank accession number | BC101511 |
Gene symbol | MEFV |
Gene ID (NCBI) | 4210 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
MEFV, a gene encoding a protein of unknown function, is the genetic cause of Familial Mediterranean fever (FMF), a recessively inherited disorder characterized by recurring attacks of fever and serositis. Recently mutation of MEFV has been reported to cause autoinflammatory disease distinct from FMF.
Protocols
Product Specific Protocols | |
---|---|
WB protocol for MEFV antibody 24280-1-AP | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |
Publications
Species | Application | Title |
---|---|---|
Exp Ther Med Function and mechanism of pyrin and IL-10 in the regulation of the inflammasome in pulmonary vascular endothelial cells following hemorrhagic shock. | ||
PLoS Biol Transcriptional licensing is required for Pyrin inflammasome activation in human macrophages and bypassed by mutations causing familial Mediterranean fever |