Product Information
17839-1-AP targets MMP16 in ELISA applications and shows reactivity with human, mouse, rat, zebrafish samples.
| Tested Reactivity | human, mouse, rat, zebrafish |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag12186 Product name: Recombinant human MMP16 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 33-400 aa of BC075005 Sequence: TVCGTEQYFNVEVWLQKYGYLPPTDPRMSVLRSAETMQSALAAMQQFYGINMTGKVDRNTIDWMKKPRCGVPDQTRGSSKFHIRRKRYALTGQKWQHKHITYSIKNVTPKVGDPETRKAIRRAFDVWQNVTPLTFEEVPYSELENGKRDVDITIIFASGFHGDSSPFDGEGGFLAHAYFPGPGIGGDTHFDSDEPWTLGNPNHDGNDLFLVAVHELGHALGLEHSNDPTAIMAPFYQYMETDNFKLPNDDLQGIQKIYGPPDKIPPPTRPLPTVPPHRSIPPADPRKNDRPKPPRPPTGRPSYPGAKPNICDGNFNTLAILRREMFVFKDQWFWRVRNNRVMDGYPMQITYFWRGLPPSIDAVYENSD Predict reactive species |
| Full Name | matrix metallopeptidase 16 (membrane-inserted) |
| Calculated Molecular Weight | 607 aa, 70 kDa |
| GenBank Accession Number | BC075005 |
| Gene Symbol | MMP16 |
| Gene ID (NCBI) | 4325 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | P51512 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
MMP16(Matrix metalloproteinase-16) is also named as MMPX2,MT3-MMP.It is an endopeptidase that degrades various components of the extracellular matrix, such as collagen type III and fibronectin.Northern blotting shows MMP16 is expressed as a 12-kb transcript in brain, placenta, heart, and some carcinoma cell lines, but is not detectably expressed in lung, kidney, liver, spleen, and muscle(PMID:7559440).And MMP16 is encountered in endothelial cells of proliferative endometrium in vivo(PMID;15531549).
