Product Information
23202-1-PBS targets MORC2 in WB, Indirect ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag19605 Product name: Recombinant human MORC2 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 617-970 aa of BC136782 Sequence: NTLVKTASRPAPLVQQLSPSLLPNSKSPREVPSPKVIKTPVVKKTESPIKLSPATPSRKRSVAVSDEEEVEEEAERRKERCKRGRFVVKEEKKDSNELSDSAGEEDSADLKRAQKDKGLHVEVRVNREWYTGRVTAVEVGKHVVRWKVKFDYVPTDTTPRDRWVEKGSEDVRLMKPPSPEHQSLDTQQEGGEEEVGPVAQQAIAVAEPSTSECLRIEPDTTALSTNHETIDLLVQILRNCLRYFLPPSFPISKKQLSAMNSDELISFPLKEYFKQYEVGLQNLCNSYQSRADSRAKASEESLRTSERKLRETEEKLQKLRTNIVALLQKVQEDIDINTDDELDAYIEDLITKGD Predict reactive species |
| Full Name | MORC family CW-type zinc finger 2 |
| Calculated Molecular Weight | 970 aa, 111 kDa |
| Observed Molecular Weight | 118 kDa |
| GenBank Accession Number | BC136782 |
| Gene Symbol | MORC2 |
| Gene ID (NCBI) | 22880 |
| RRID | AB_3669412 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q9Y6X9 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
MORC2 is essential for epigenetic silencing by the HUSH (human silencing hub) complex. It can be recruited by HUSH to target site in heterochromatin. MORC2 also recruits histone deacetylases, such as HDAC4, to promoter regions, causing local histone H3 deacetylation and transcriptional repression of genes.
