Product Information
13158-1-AP targets MPZL1 (BC019890, 147aa) in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag3791 Product name: Recombinant human MPZL1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-147 aa of BC019890 Sequence: MTPGGLFLPYHSLPQPDFLASCPTRHLKLCQCPGILAENPHQFSPTFPPGKGSCQHGALPGQVSLKEAAHTEMSLSGQDLFPSPAHPPLQPFWLPFSLCLSTPFLVADNELRLPKGQICPLHVFVLANRVVLKLCANSVWEHSKGIT Predict reactive species |
| Full Name | myelin protein zero-like 1 |
| Calculated Molecular Weight | 147 aa, 16 kDa |
| Observed Molecular Weight | 16 kDa |
| GenBank Accession Number | BC019890 |
| Gene Symbol | MPZL1 |
| Gene ID (NCBI) | 9019 |
| RRID | AB_2144774 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | O95297 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
Myelin protein zero-like 1 (MPZL1), also known as Protein zero-related, is a transmembrane glycoprotein involved in extracellular matrix-induced signal transduction (PMID: 9792637; 11751924). Its extracellular segment has significant sequence homology to myelin P0, whereas its intracellular portion has two tyrosine phosphorylation sites resembling ITIMs (PMID: 9792637). Alternative splicing of the MPZL1 gene results in multiple transcript variants encoding different isoforms. This antibody raised against MPZL1 (BC019890, 147aa).
Publications
What published studies show
The MPZL1 (BC019890, 147aa) Polyclonal antibody (Cat# 13158-1-AP) has 1 citation. It appears in Onco Targets Ther (2020), where the antibody was used in Western blot to study how long non-coding RNA SPRY4-IT1 reverses cisplatin resistance by downregulating MPZL-1 via EMT suppression in non-small cell lung cancer (NSCLC). The associated research field is oncology, specifically lung cancer and epithelial-mesenchymal transition.
| Species | Application | Title |
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