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  • KD/KO Validated

MTX1 Polyclonal antibody

MTX1 Polyclonal Antibody for WB, IP, ELISA

Host / Isotype

Rabbit / IgG


human and More (1)





Cat no : 15529-1-AP


metaxin 1, MTX, MTX1, MTXN

Tested Applications

Positive WB detected inHepG2 cells, A549 cells, Jurkat cells, HeLa cells
Positive IP detected inMCF-7 cells

Recommended dilution

Western Blot (WB)WB : 1:500-1:1000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

15529-1-AP targets MTX1 in WB, IP, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Cited Reactivityhuman, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen MTX1 fusion protein Ag7685
Full Name metaxin 1
Calculated Molecular Weight 51 kDa
Observed Molecular Weight 35 kDa
GenBank Accession NumberBC001906
Gene Symbol MTX1
Gene ID (NCBI) 4580
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

METAXINs are proteins located in the outer membrane of the mammalian mitochondrion. METAXIN 1 was characterized firstly and was found to play a role in the import of mitochondrial precursor proteins. It may also play a role in the assembly of b-barrel proteins into the outer membrane METAXIN1 was reported to be essential for survival of the postimplantation mouse embryo. METAXIN 1 has multiple transcripts. Several isoforms of METAXIN 1 exist due to the alternative splicing, with the predicted MW of 51, 48 and 36 kDa, respectively. Metaxin 1 interacts with metaxin 2, a novel related protein associated with the mammalian mitochondrial outer membrane and form complex in the mitochondrion outer membrane.


Product Specific Protocols
WB protocol for MTX1 antibody 15529-1-APDownload protocol
IP protocol for MTX1 antibody 15529-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols



Int J Biol Sci

Genome-scale CRISPRa screening identifies MTX1 as a contributor for sorafenib resistance in hepatocellular carcinoma by augmenting autophagy.

Authors - Li Li
  • KD Validated


Loss of Sam50 in hepatocytes induces cardiolipin-dependent mitochondrial membrane remodeling to trigger mtDNA release and liver injury

Authors - Li Chen

J Cell Sci

Myo19 tethers mitochondria to endoplasmic reticulum-associated actin to promote mitochondrial fission

Authors - Stephen M Coscia
  • KD Validated